CARBOXAMIDOTHIAZOLE DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula:in which R1 is a substituted phenyl group, R2 is a group chosen from CH2-R7, (CH2)2-R7, S-CH2-R7, CH2-S-R7 and (C5-C8)alkyl with R7 being a (C5-C7)cycloalkyl group, and R3 is a groupwith R8 being a group...

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Hauptverfasser: JEANARLES MOLIMARD, ROBERT BOIGEGRAIN, DOMINIGUE OLLIERO, ERIC BIGNON, ROGER BRODIN
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creator JEANARLES MOLIMARD
ROBERT BOIGEGRAIN
DOMINIGUE OLLIERO
ERIC BIGNON
ROGER BRODIN
description The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula:in which R1 is a substituted phenyl group, R2 is a group chosen from CH2-R7, (CH2)2-R7, S-CH2-R7, CH2-S-R7 and (C5-C8)alkyl with R7 being a (C5-C7)cycloalkyl group, and R3 is a groupwith R8 being a group (CH2)nR15 orand R15 being COOH or COO(C1-C4)alkyl. The invention also relates to a process for the preparation of the pharmaceutical compositions containing them and to their uses for the preparation of medicines.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CARBOXAMIDOTHIAZOLE DERIVATIVES, PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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