COMPOSICIONES FARMACEUTICAS DE MESILATO DE ZONIPORIDA Y PROCEDIMIENTOS PARA MEJORAR LA SOLUBILIDAD DE LA ZONIPORIDA

LA PRESENTE INVENCION SE REFIERE A FORMULACIONESLIOFILIZADAS QUE CONTIENEN LA SAL MESILATO DEL COMPUESTO DE LA FORMULA I, N-(5-CICLOPROPIL-1-QUINOLIN-5-IL-1H-PIRAZOL-4-CARBONIL)-GUANIDINA, (DE AQUI EN ADELANTE "ZONIPORIDA"). Formulations containing a sodium hydrogen exchanger-1 (NHE-1) inh...

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1. Verfasser: DANIEL RAY ARENSON
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description LA PRESENTE INVENCION SE REFIERE A FORMULACIONESLIOFILIZADAS QUE CONTIENEN LA SAL MESILATO DEL COMPUESTO DE LA FORMULA I, N-(5-CICLOPROPIL-1-QUINOLIN-5-IL-1H-PIRAZOL-4-CARBONIL)-GUANIDINA, (DE AQUI EN ADELANTE "ZONIPORIDA"). Formulations containing a sodium hydrogen exchanger-1 (NHE-1) inhibitor for prevention of, inter alia, perioperative myocardial ischemic injury in mammals and a process for increasing the solubility of said inhibitor with methanesulfonic acid.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSICIONES FARMACEUTICAS DE MESILATO DE ZONIPORIDA Y PROCEDIMIENTOS PARA MEJORAR LA SOLUBILIDAD DE LA ZONIPORIDA
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