SYNTHESIS OF BACE1 INHIBITORS BACE

The present invention provides a one step carbonylation of a compound of formula II in the presence of water to afford a compound of formula (I), useful in processes to manufacture BACE inhibitors.

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Bibliographische Detailangaben
Hauptverfasser: FETTES, Alec, MARTY, Hans-Peter, SCALONE, Michelangelo
Format: Patent
Sprache:chi ; eng
Schlagworte:
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Beschreibung
Zusammenfassung:The present invention provides a one step carbonylation of a compound of formula II in the presence of water to afford a compound of formula (I), useful in processes to manufacture BACE inhibitors.