INHIBITORS OF BETA SECRETASE

The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the -secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders character...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	DILLARD, LAWERANCE, WAYNE, FUCHS, KLAUS, DORNER-CIOSSEK, CORNELIA, YUAN, JING, HEINE, NIKLAS, SINGH, SURESH, B, BUKHTIYAROV, YURI, XU, ZHENRONG, VENKATRAMAN, SHANKAR, GROSS, ULIKE, ZHENG, YAJUN, JIA, LANQI, SAUER, ACHIM, MORALES-RAMOS, ANGEL, ZHAO, YI, LALA, DEEPAK, S, CACATIAN, SALVACION
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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