METHOD FOR THE SELECTION AND PRODUCTION OF TAILOR-MADE, SELECTIVE AND MULTI-SPECIFIC THERAPEUTIC MOLECULES COMPRISING AT LEAST TWO DIFFERENT TARGETING ENTITIES AND USES THEREOF

Herein is reported a method for determining a combination of antigen binding sites comprising the steps of (i) determining the binding specificity and/or affinity and/or effector function and/or in vivo half-life of a multitude of bispecific antibodies prepared by combining each member of a first mu...

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Bibliographische Detailangaben
Hauptverfasser: TIEFENTHALER, GEORG, KALUZA, BRIGITTE, HUELSMANN, PETER, MICHAEL, HEINDL, DIETER, KOPETZKI, ERHARD, NIEDERFELLNER, GERHARD
Format: Patent
Sprache:chi ; eng
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