INHIBITORS OF BETA SECRETASE

The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characte...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	Suresh B. SINGH SB, Jing YUAN, Yi ZHAO, Lawrence Wayne DILLARD LW, Deepak S. LALA DS, Georg RAST G, Klaus FUCHS K, Cornelia DORNER-CIOSSEK C, Jonathan REEVES J, Shankar VENKATRAMAN S, Yajun ZHENG, Salvacion CACATIAN S, Zhenrong XU, Lanqi JIA, Angel MORALES-RAMOS A, Yuri BUKHTIYAROV Y
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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