INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, o...

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Hauptverfasser: BHATTACHARYA, SAMIT KUMAR SK, SMITH, AARON CHRISTOPHER AC, FILIPSKI, KEVIN JAMES KJ, CAMERON, KIMBERLY OKEEFE KO, FERNANDO, DILINIE PRASADHINI DP, KUNG, DANIEL WEI-SHUNG DW-S, EBNER, DAVID CHRISTOPHER DC, LEE, ESTHER CHENG YIN ECY, DOWLING, MATTHEW SCOTT MS, TU, MEIHUA MIKE MM
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creator BHATTACHARYA, SAMIT KUMAR SK
SMITH, AARON CHRISTOPHER AC
FILIPSKI, KEVIN JAMES KJ
CAMERON, KIMBERLY OKEEFE KO
FERNANDO, DILINIE PRASADHINI DP
KUNG, DANIEL WEI-SHUNG DW-S
EBNER, DAVID CHRISTOPHER DC
LEE, ESTHER CHENG YIN ECY
DOWLING, MATTHEW SCOTT MS
TU, MEIHUA MIKE MM
description The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK AMPK
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