ANTICANCER FUSION PROTEIN

A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity, preferably 85% identity and ending with th...

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Hauptverfasser: PIECZYKOLAN, JERZY SZCZEPAN, ZEREK, BARTLOMIEJ MACIEJ, PIECZYKOLAN, ANNA MARIA, PAWLAK, SEBASTIAN, SZYMANIK, MICHAL, ROZGA, PIOTR, JAWORSKI, ALBERT ROBERT, TESKA-KAMINSKA, MALGORZATA IZABELA
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creator PIECZYKOLAN, JERZY SZCZEPAN
ZEREK, BARTLOMIEJ MACIEJ
PIECZYKOLAN, ANNA MARIA
PAWLAK, SEBASTIAN
SZYMANIK, MICHAL
ROZGA, PIOTR
JAWORSKI, ALBERT ROBERT
TESKA-KAMINSKA, MALGORZATA IZABELA
description A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity, preferably 85% identity and ending with the amino acid hTRAIL281; and domain (b) which is a sequence of an effector peptide inhibiting protein synthesis, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
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language chi ; eng
recordid cdi_epo_espacenet_HK1201727A1
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ANTICANCER FUSION PROTEIN
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