APPARATUS FOR LUMINESCENCE ASSAYS

The invention relates to an apparatus for performing a binding assay for an analyte of interest in a sample based upon measurement of electro-chemiluminescence at an electrode surface comprising an electrochemical cell having a sample-holding volume, inlet and outlet means; a working electrode syste...

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Hauptverfasser: BLACKBURN GARY F, LELAND JOHN K, SHAH HARESH P, LOWKE GEORGE E, MASSEY RICHARD J, GOODMAN JACK E, KENTEN JOHN H
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Sprache:eng
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creator BLACKBURN GARY F
LELAND JOHN K
SHAH HARESH P
LOWKE GEORGE E
MASSEY RICHARD J
GOODMAN JACK E
KENTEN JOHN H
description The invention relates to an apparatus for performing a binding assay for an analyte of interest in a sample based upon measurement of electro-chemiluminescence at an electrode surface comprising an electrochemical cell having a sample-holding volume, inlet and outlet means; a working electrode system to provide electrochemical energy to trigger electrochemiluminescence; a voltage control device to supply voltage signals to the working electrode system; a magnet placed in proper orientation and in close proximity to the working electrode so that magnetically responsive particles will concentrate on the surface of the working electrode; a light detection/measurement device for measuring electrochemiluminescence triggered at the electrode surface; and a pump to provide for fluid transport to, through and from the electrochemical cell. The apparatus may be used in an electrochemiluminescence assay for an analyte of interest in which magnetically responsive particles are magnetically collected on the electrode surface and emitted electrochemiluminescence is measured using the light detector.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
DERIVATIVES THEREOF
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
SUGARS
TESTING
VINEGAR
WINE
title APPARATUS FOR LUMINESCENCE ASSAYS
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