Reversible gelling system for ocular drug delivery
The invention provides an ophthalmic aqueous composition for topical administration, comprising:(a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide viscosity of less than about 25 centipoise at ambient temperature and viscosity of from about 25 to about...
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| creator | SMERBECK, RICHARD, V ERNING XIA |
| description | The invention provides an ophthalmic aqueous composition for topical administration, comprising:(a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide viscosity of less than about 25 centipoise at ambient temperature and viscosity of from about 25 to about 55 centipoise when applied topically to a patient;(b) hydroxypropyl methylcellulose in concentration sufficient to improve the durability of the gel formed by the block copolymer.The invention further provides a method for administering ophthalmic pharmaceuticals. |
| format | Patent |
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STENTS ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROSTHESES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040716&DB=EPODOC&CC=HK&NR=1059728A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040716&DB=EPODOC&CC=HK&NR=1059728A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SMERBECK, RICHARD, V</creatorcontrib><creatorcontrib>ERNING XIA</creatorcontrib><title>Reversible gelling system for ocular drug delivery</title><description>The invention provides an ophthalmic aqueous composition for topical administration, comprising:(a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide viscosity of less than about 25 centipoise at ambient temperature and viscosity of from about 25 to about 55 centipoise when applied topically to a patient;(b) hydroxypropyl methylcellulose in concentration sufficient to improve the durability of the gel formed by the block copolymer.The invention further provides a method for administering ophthalmic pharmaceuticals.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROSTHESES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAKSi1LLSrOTMpJVUhPzcnJzEtXKK4sLknNVUjLL1LITy7NSSxSSCkqTVdISc3JBKqt5GFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8R7ehgamluZGFo6GxkQoAQCWxyv6</recordid><startdate>20040716</startdate><enddate>20040716</enddate><creator>SMERBECK, RICHARD, V</creator><creator>ERNING XIA</creator><scope>EVB</scope></search><sort><creationdate>20040716</creationdate><title>Reversible gelling system for ocular drug delivery</title><author>SMERBECK, RICHARD, V ; ERNING XIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HK1059728A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2004</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. 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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROSTHESES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TREATMENT OR PROTECTION OF EYES OR EARS |
| title | Reversible gelling system for ocular drug delivery |
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