Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides

Phosphoramidites of the formula where R is a base-labile protecting group, R and R are individually alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, or aryl of 6 to 20 carbon atoms or are joined together to form with the nitrogen atom a cyclic structure of 4-7 carbon atoms and 0 to 1...

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Hauptverfasser:	STEPHEN COUTTS, DAVID S. JONES, JOHN P. HACHMANN, DOUGLAS ALAN LIVINGSTON, MICHAEL J. CONRAD
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
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