POLIMORFO DE BROMURO DE (R)-3-(2-HIDROXI-2,2-DIFENIL-ACETOXI)-1-(ISOXAZOL-3-IL-CARBAMOIL-METIL)-1-AZONIA-BICICLO-[2.2.2]-OCTANO

UNA FORMA DE CRISTAL POLIMÓRFICO NOVEDOSA DE BROMURO DE (R)-3-(2-HIDROXI-2.2-DIFENIL-ACETOXI)-1-(ISOXAZOL-3-IL-CARBAMOIL-METIL)-1-AZONIA-BICICLO-(2.2.2)-OCTANO, DESIGNADA COMO LA FORMA DEL CRISTAL TALFA. TAMBIÉN SE DESCRIBEN MÉTODOS PARA LA PREPARACIÓN DE LA MISMA, Y EL USO DE LA FORMA DEL CRISTAL C...

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MUHRER, GERHARD
description UNA FORMA DE CRISTAL POLIMÓRFICO NOVEDOSA DE BROMURO DE (R)-3-(2-HIDROXI-2.2-DIFENIL-ACETOXI)-1-(ISOXAZOL-3-IL-CARBAMOIL-METIL)-1-AZONIA-BICICLO-(2.2.2)-OCTANO, DESIGNADA COMO LA FORMA DEL CRISTAL TALFA. TAMBIÉN SE DESCRIBEN MÉTODOS PARA LA PREPARACIÓN DE LA MISMA, Y EL USO DE LA FORMA DEL CRISTAL COMO EL INGREDIENTE ACTIVO DE MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS U OBSTRUCTIVAS DE LAS VÍAS RESPIRATORIAS. A novel polymorphic crystal form of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide, designated crystal form Talpha. Methods for preparing same and the use of the crystal form as the active ingredient of medicaments for the treatment of inflammatory or obstructive airways diseases are also described.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title POLIMORFO DE BROMURO DE (R)-3-(2-HIDROXI-2,2-DIFENIL-ACETOXI)-1-(ISOXAZOL-3-IL-CARBAMOIL-METIL)-1-AZONIA-BICICLO-[2.2.2]-OCTANO
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