COMPUESTOS DE HETEROARIL- Y FENILSULFAMOILO SUSTITUIDOS
LA PRESENTE INVENICION SE REFIERE A COMPUESTOS HETEROARIL Y AL USO DE TALES COMPUESTOS COMO AGONISTAS DEL RECEPTOR ACTIVADOR DEL PROLIFERADOR DE PEROXISOMA (PPAR). LOS ACTIVADORES PPAR ALFA, COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y EL USO DE TALES COMPUESTOS SON UTILES PARA ELEVA...
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| creator | ERNEST SEIICHI HAMANAKA |
| description | LA PRESENTE INVENICION SE REFIERE A COMPUESTOS HETEROARIL Y AL USO DE TALES COMPUESTOS COMO AGONISTAS DEL RECEPTOR ACTIVADOR DEL PROLIFERADOR DE PEROXISOMA (PPAR). LOS ACTIVADORES PPAR ALFA, COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y EL USO DE TALES COMPUESTOS SON UTILES PARA ELEVAR CIERTOS NIVELES DE LIPIDOS EN PLASMA, INCLUYENDO COLESTEROLLIPOPROTEINA DE ALTA DESNSIDAD Y PARA REDUCIR CIERTOS NIVELES DE LIPIDOS DISTINTOS EN PLASMA TALES COMO COLESTEROLLDL Y TRIGLICERIDOS Y POR CONSIGUIENTE PARA TRATAR ENFERMEDADES QUE EMPEORAN CON BAJOS NIVELES DE COLESTEROL HDL Y/O ALTOS NIVELES DE COLESTEROLLDL Y TRIGLICERIDOS TALES COMO ARTEROSCLEROSIS Y ENFERMEDADES CARDIOVASCULARES EN MAMIFEROS, INCLUYENDO SERES HUMANOS. LOS COMPUESTOS TAMBIEN SON UTILES PARA EL TRATAMIENTO DEL BALANCE ENERGETICO NEGATIVO (NEB) Y ENFERMEDADES ASOCIADAS EN RUMIANTES. T2005
The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants. |
| format | Patent |
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The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.</description><language>spa</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060302&DB=EPODOC&CC=GT&NR=200500173A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060302&DB=EPODOC&CC=GT&NR=200500173A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ERNEST SEIICHI HAMANAKA</creatorcontrib><title>COMPUESTOS DE HETEROARIL- Y FENILSULFAMOILO SUSTITUIDOS</title><description>LA PRESENTE INVENICION SE REFIERE A COMPUESTOS HETEROARIL Y AL USO DE TALES COMPUESTOS COMO AGONISTAS DEL RECEPTOR ACTIVADOR DEL PROLIFERADOR DE PEROXISOMA (PPAR). LOS ACTIVADORES PPAR ALFA, COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y EL USO DE TALES COMPUESTOS SON UTILES PARA ELEVAR CIERTOS NIVELES DE LIPIDOS EN PLASMA, INCLUYENDO COLESTEROLLIPOPROTEINA DE ALTA DESNSIDAD Y PARA REDUCIR CIERTOS NIVELES DE LIPIDOS DISTINTOS EN PLASMA TALES COMO COLESTEROLLDL Y TRIGLICERIDOS Y POR CONSIGUIENTE PARA TRATAR ENFERMEDADES QUE EMPEORAN CON BAJOS NIVELES DE COLESTEROL HDL Y/O ALTOS NIVELES DE COLESTEROLLDL Y TRIGLICERIDOS TALES COMO ARTEROSCLEROSIS Y ENFERMEDADES CARDIOVASCULARES EN MAMIFEROS, INCLUYENDO SERES HUMANOS. LOS COMPUESTOS TAMBIEN SON UTILES PARA EL TRATAMIENTO DEL BALANCE ENERGETICO NEGATIVO (NEB) Y ENFERMEDADES ASOCIADAS EN RUMIANTES. T2005
The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB39vcNCHUNDvEPVnBxVfBwDXEN8ncM8vTRVYhUcHP18_QJDvVxc_T19_TxVwgODQ7xDAn1dPEP5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8e4hRgYGpgYGhubGjsbEqAEAa-Aonw</recordid><startdate>20060302</startdate><enddate>20060302</enddate><creator>ERNEST SEIICHI HAMANAKA</creator><scope>EVB</scope></search><sort><creationdate>20060302</creationdate><title>COMPUESTOS DE HETEROARIL- Y FENILSULFAMOILO SUSTITUIDOS</title><author>ERNEST SEIICHI HAMANAKA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GT200500173A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2006</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ERNEST SEIICHI HAMANAKA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ERNEST SEIICHI HAMANAKA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPUESTOS DE HETEROARIL- Y FENILSULFAMOILO SUSTITUIDOS</title><date>2006-03-02</date><risdate>2006</risdate><abstract>LA PRESENTE INVENICION SE REFIERE A COMPUESTOS HETEROARIL Y AL USO DE TALES COMPUESTOS COMO AGONISTAS DEL RECEPTOR ACTIVADOR DEL PROLIFERADOR DE PEROXISOMA (PPAR). LOS ACTIVADORES PPAR ALFA, COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y EL USO DE TALES COMPUESTOS SON UTILES PARA ELEVAR CIERTOS NIVELES DE LIPIDOS EN PLASMA, INCLUYENDO COLESTEROLLIPOPROTEINA DE ALTA DESNSIDAD Y PARA REDUCIR CIERTOS NIVELES DE LIPIDOS DISTINTOS EN PLASMA TALES COMO COLESTEROLLDL Y TRIGLICERIDOS Y POR CONSIGUIENTE PARA TRATAR ENFERMEDADES QUE EMPEORAN CON BAJOS NIVELES DE COLESTEROL HDL Y/O ALTOS NIVELES DE COLESTEROLLDL Y TRIGLICERIDOS TALES COMO ARTEROSCLEROSIS Y ENFERMEDADES CARDIOVASCULARES EN MAMIFEROS, INCLUYENDO SERES HUMANOS. LOS COMPUESTOS TAMBIEN SON UTILES PARA EL TRATAMIENTO DEL BALANCE ENERGETICO NEGATIVO (NEB) Y ENFERMEDADES ASOCIADAS EN RUMIANTES. T2005
The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPUESTOS DE HETEROARIL- Y FENILSULFAMOILO SUSTITUIDOS |
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