COMPUESTOS PIRAZOL-TIAZOL, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU MODO DE EMPLEO PARA INHIBIR QUINASASCICLINO-DEPENDIENTES
EN LA PRESENTE INVENCION SE DESCRIBEN COMPUESTOS DE PIRAZOLDIAZOL, QUE MODULAN O INHIBEN LA ACTIVIDAD DE LAS QUINASAS CICLINODEPEDIENTES. ESTOS COMPUESTOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN SON CAPACES DE MEDIAR ENENFERMEDADES CICLINODEPENDIENTES PARA MODULAR O INHIBIR LA PROLIFARCI...
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| creator | ROHIT KUMAR DUVADIE WESLEY KWAN MUNG CHONG |
| description | EN LA PRESENTE INVENCION SE DESCRIBEN COMPUESTOS DE PIRAZOLDIAZOL, QUE MODULAN O INHIBEN LA ACTIVIDAD DE LAS QUINASAS CICLINODEPEDIENTES. ESTOS COMPUESTOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN SON CAPACES DE MEDIAR ENENFERMEDADES CICLINODEPENDIENTES PARA MODULAR O INHIBIR LA PROLIFARCION INDESEADA DE CELULAS. EL INVENTO ESTA TAMBIEN DIRIGIDO AL USO TERAPEUTICO O PROFILACTICO DE COMPOSICIONES FARMACEUTICAS QUE CONTIENE DICHOS COMPUESTOS, Y A METODOS PRA TRATAR EL CANCER ASI COMO OTROS ESTADOS DE ENFERMEDAD ASOCIADOS CON ANGIOGENESIS INDESEADA O PROLIFERACION CELULAR, TALES COMO RETINOPATIA DIABETICA, GLAUCOMA NEOVASCULAR, ARTRITIS REUMATOIDE, Y PSORIASIS, POR MEDIO DE LA ADMINISTRACION DE CANTIDADES EFICACES DE DICHOS COMPUESTOS.
Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds. |
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Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.</description><edition>6</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20020516&DB=EPODOC&CC=GT&NR=200100162A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20020516&DB=EPODOC&CC=GT&NR=200100162A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROHIT KUMAR DUVADIE</creatorcontrib><creatorcontrib>WESLEY KWAN MUNG CHONG</creatorcontrib><title>COMPUESTOS PIRAZOL-TIAZOL, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU MODO DE EMPLEO PARA INHIBIR QUINASASCICLINO-DEPENDIENTES</title><description>EN LA PRESENTE INVENCION SE DESCRIBEN COMPUESTOS DE PIRAZOLDIAZOL, QUE MODULAN O INHIBEN LA ACTIVIDAD DE LAS QUINASAS CICLINODEPEDIENTES. ESTOS COMPUESTOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN SON CAPACES DE MEDIAR ENENFERMEDADES CICLINODEPENDIENTES PARA MODULAR O INHIBIR LA PROLIFARCION INDESEADA DE CELULAS. EL INVENTO ESTA TAMBIEN DIRIGIDO AL USO TERAPEUTICO O PROFILACTICO DE COMPOSICIONES FARMACEUTICAS QUE CONTIENE DICHOS COMPUESTOS, Y A METODOS PRA TRATAR EL CANCER ASI COMO OTROS ESTADOS DE ENFERMEDAD ASOCIADOS CON ANGIOGENESIS INDESEADA O PROLIFERACION CELULAR, TALES COMO RETINOPATIA DIABETICA, GLAUCOMA NEOVASCULAR, ARTRITIS REUMATOIDE, Y PSORIASIS, POR MEDIO DE LA ADMINISTRACION DE CANTIDADES EFICACES DE DICHOS COMPUESTOS.
Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNizEKwkAQRdNYiHqHsTcQFezH3YkZSHbWzKbQJgRZK9FAPIPnNgEPIHx4xX9vnnyMVL4hDaLgucarlGngCRuYLlE2LI4UcqwrNNQENqhwbgjKsTHiApMjBxfQBiqxApaAKl-SgMcagV3BR67HhB0qqmFTspPUkidnxziQLpPZvXsMcfXjIlnnFEyRxv7VxqHvbvEZ3-0p7LJsO-6ww_0_zhc0tD42</recordid><startdate>20020516</startdate><enddate>20020516</enddate><creator>ROHIT KUMAR DUVADIE</creator><creator>WESLEY KWAN MUNG CHONG</creator><scope>EVB</scope></search><sort><creationdate>20020516</creationdate><title>COMPUESTOS PIRAZOL-TIAZOL, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU MODO DE EMPLEO PARA INHIBIR QUINASASCICLINO-DEPENDIENTES</title><author>ROHIT KUMAR DUVADIE ; WESLEY KWAN MUNG CHONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GT200100162A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2002</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ROHIT KUMAR DUVADIE</creatorcontrib><creatorcontrib>WESLEY KWAN MUNG CHONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROHIT KUMAR DUVADIE</au><au>WESLEY KWAN MUNG CHONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPUESTOS PIRAZOL-TIAZOL, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU MODO DE EMPLEO PARA INHIBIR QUINASASCICLINO-DEPENDIENTES</title><date>2002-05-16</date><risdate>2002</risdate><abstract>EN LA PRESENTE INVENCION SE DESCRIBEN COMPUESTOS DE PIRAZOLDIAZOL, QUE MODULAN O INHIBEN LA ACTIVIDAD DE LAS QUINASAS CICLINODEPEDIENTES. ESTOS COMPUESTOS Y LAS COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN SON CAPACES DE MEDIAR ENENFERMEDADES CICLINODEPENDIENTES PARA MODULAR O INHIBIR LA PROLIFARCION INDESEADA DE CELULAS. EL INVENTO ESTA TAMBIEN DIRIGIDO AL USO TERAPEUTICO O PROFILACTICO DE COMPOSICIONES FARMACEUTICAS QUE CONTIENE DICHOS COMPUESTOS, Y A METODOS PRA TRATAR EL CANCER ASI COMO OTROS ESTADOS DE ENFERMEDAD ASOCIADOS CON ANGIOGENESIS INDESEADA O PROLIFERACION CELULAR, TALES COMO RETINOPATIA DIABETICA, GLAUCOMA NEOVASCULAR, ARTRITIS REUMATOIDE, Y PSORIASIS, POR MEDIO DE LA ADMINISTRACION DE CANTIDADES EFICACES DE DICHOS COMPUESTOS.
Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPUESTOS PIRAZOL-TIAZOL, COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN Y SU MODO DE EMPLEO PARA INHIBIR QUINASASCICLINO-DEPENDIENTES |
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