Soluble salts of 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide, process for their preparation, their use as medicine and initial products

Soluble salts of 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide, process for their preparation, their use as medicine and initial products

Water-soluble and easily soluble salts of 4-amino-2-(4,4-dimethyl-imidazolin-2-on-1-yl)-pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide and a process for their preparation. The compounds are suitable for treatment of lipid metabolism disturbances which are favourably influen...

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Hauptverfasser: HUETTINGER, MANFRED, DR, LEINEWEBER, MICHAEL, KAMPE, KLAUS-DIETER, GRANZER, ERNOLDDR
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator HUETTINGER, MANFRED, DR
LEINEWEBER, MICHAEL
KAMPE, KLAUS-DIETER
GRANZER, ERNOLDDR
description Water-soluble and easily soluble salts of 4-amino-2-(4,4-dimethyl-imidazolin-2-on-1-yl)-pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide and a process for their preparation. The compounds are suitable for treatment of lipid metabolism disturbances which are favourably influenced by stimulating the hepatic LDL-receptor. The compounds of the formula IV and their salts are also described.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Soluble salts of 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-1-yl)-pyrimidin-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide, process for their preparation, their use as medicine and initial products
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