Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments

Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments

The present invention relates to various derivatives related to physostigmine of the formula I where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HAMER, RUSSELL RICHARD LEE, GLAMKOWSKI, EDWARD JOSEPH, CHIANG, YULIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator HAMER, RUSSELL RICHARD LEE
GLAMKOWSKI, EDWARD JOSEPH
CHIANG, YULIN
description The present invention relates to various derivatives related to physostigmine of the formula I where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds according to the invention are useful for enhancing cholinergic function, and as analgesic agents.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_GR3021210TT3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>GR3021210TT3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_GR3021210TT33</originalsourceid><addsrcrecordid>eNqNyrsKwkAQRuE0FqK-w9gr5PIEIl5qSS_j5o9ZyO4sO2ORtzdCHsDqg8NZF_EUfBTH-SVxGn9yYINSxjjbkQmlYVJR8-95xYGYUhYHVeolkw3weS5InNm8ROLYLfWjIFYK6LzjgGi6LVY9j4rd4qbYXy_t-X5Ekic0sUOEPW-Ppqyruirbtmn-eb4-c0OR</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments</title><source>esp@cenet</source><creator>HAMER, RUSSELL RICHARD LEE ; GLAMKOWSKI, EDWARD JOSEPH ; CHIANG, YULIN</creator><creatorcontrib>HAMER, RUSSELL RICHARD LEE ; GLAMKOWSKI, EDWARD JOSEPH ; CHIANG, YULIN</creatorcontrib><description>The present invention relates to various derivatives related to physostigmine of the formula I where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds according to the invention are useful for enhancing cholinergic function, and as analgesic agents.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19961231&amp;DB=EPODOC&amp;CC=GR&amp;NR=3021210T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19961231&amp;DB=EPODOC&amp;CC=GR&amp;NR=3021210T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAMER, RUSSELL RICHARD LEE</creatorcontrib><creatorcontrib>GLAMKOWSKI, EDWARD JOSEPH</creatorcontrib><creatorcontrib>CHIANG, YULIN</creatorcontrib><title>Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments</title><description>The present invention relates to various derivatives related to physostigmine of the formula I where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds according to the invention are useful for enhancing cholinergic function, and as analgesic agents.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrsKwkAQRuE0FqK-w9gr5PIEIl5qSS_j5o9ZyO4sO2ORtzdCHsDqg8NZF_EUfBTH-SVxGn9yYINSxjjbkQmlYVJR8-95xYGYUhYHVeolkw3weS5InNm8ROLYLfWjIFYK6LzjgGi6LVY9j4rd4qbYXy_t-X5Ekic0sUOEPW-Ppqyruirbtmn-eb4-c0OR</recordid><startdate>19961231</startdate><enddate>19961231</enddate><creator>HAMER, RUSSELL RICHARD LEE</creator><creator>GLAMKOWSKI, EDWARD JOSEPH</creator><creator>CHIANG, YULIN</creator><scope>EVB</scope></search><sort><creationdate>19961231</creationdate><title>Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments</title><author>HAMER, RUSSELL RICHARD LEE ; GLAMKOWSKI, EDWARD JOSEPH ; CHIANG, YULIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GR3021210TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1996</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HAMER, RUSSELL RICHARD LEE</creatorcontrib><creatorcontrib>GLAMKOWSKI, EDWARD JOSEPH</creatorcontrib><creatorcontrib>CHIANG, YULIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HAMER, RUSSELL RICHARD LEE</au><au>GLAMKOWSKI, EDWARD JOSEPH</au><au>CHIANG, YULIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments</title><date>1996-12-31</date><risdate>1996</risdate><abstract>The present invention relates to various derivatives related to physostigmine of the formula I where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds according to the invention are useful for enhancing cholinergic function, and as analgesic agents.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_GR3021210TT3
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T05%3A08%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HAMER,%20RUSSELL%20RICHARD%20LEE&rft.date=1996-12-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EGR3021210TT3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true