Pharmaceutical composition and a method for manufacturing the same

Pharmaceutical composition and a method for manufacturing the same

Pharmaceutical compositions comprising omeprazole, with an improved shelf-life, and a method for manufacturing the same. Also claimed is a vehicle which comprises a viscosity enhancing component, a wetting agent, a pH buffer and a polyol. A pharmaceutical composition is also disclosed, comprising th...

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Hauptverfasser: Mahboob Ur Rehman, Waseem Ahmad
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Mahboob Ur Rehman
Waseem Ahmad
description Pharmaceutical compositions comprising omeprazole, with an improved shelf-life, and a method for manufacturing the same. Also claimed is a vehicle which comprises a viscosity enhancing component, a wetting agent, a pH buffer and a polyol. A pharmaceutical composition is also disclosed, comprising the aforementioned vehicle and an active pharmaceutical ingredient, such as omeprazole. Further, a method of manufacturing the same comprises the steps of mixing a viscosity enhancing component with a wetting agent to form a mixture and adding a pH buffer and a polyol to the mixture to form a vehicle. In a preferred embodiment of the vehicle, the viscosity enhancing component is sodium carboxymethyl cellulose, the wetting agent is propylene glycol, the pH buffer is sodium bicarbonate and the polyol is maltitol.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical composition and a method for manufacturing the same
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