Smoking article

A smoking article, the article comprises an oxidase enzyme. Preferably one or more redox mediators of an enzyme-redox mediator system are incorporated into the smoking article in addition to one or more co-substrates of the oxidase enzyme. The oxidase enzyme may be immobilized with respect to a solid support. Preferably, the oxidase enzyme is incorporated into a filter or filter element of the smoking article and may be contained inside an additive release component such as a breakable capsule. Preferably, the oxidase enzyme removes one or more chemical substances from tobacco smoke without modifying the concentration of nicotine contained in the tobacco smoke. The oxidase enzyme may be a laccase enzyme and may be derived from tobacco. Advantageously the smoking article is capable of removing chemical substances from an aerosol generated by the smoking article.