THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME
The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl o...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ZOLTAN GYORGYDEAK REZSO BOGNAR GEZA HORVATH ISTVAN KOVACS ATTILA JAKAB TEREZIA MILE ILDIKO MIHOK MARIANN FEKETE JANOS BALINT JUDIT KRUSPER FERENC PUSZTAI KAROLY LAPIS ANDRAS JENEI BELA SZENDE SANDOR JANCSO |
| description | The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_GB2177089B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>GB2177089B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_GB2177089B3</originalsourceid><addsrcrecordid>eNrjZHAL8fB0jPL38XTx9HN1dgxy8o-I9PF0VnB09nRRcHEN8gxzDPEMcw1WcPRzUQgI8nd2DQ5WcPMPArJdAxyDPP3cFYIdfV15GFjTEnOKU3mhNDeDvJtriLOHbmpBfnxqcUFicmpeakm8u5ORobm5gYWlkzFhFQAkxiux</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME</title><source>esp@cenet</source><creator>ZOLTAN GYORGYDEAK ; REZSO BOGNAR ; GEZA HORVATH ; ISTVAN KOVACS ; ATTILA JAKAB ; TEREZIA MILE ; ILDIKO MIHOK ; MARIANN FEKETE ; JANOS BALINT ; JUDIT KRUSPER ; FERENC PUSZTAI ; KAROLY LAPIS ; ANDRAS JENEI ; BELA SZENDE ; SANDOR JANCSO</creator><creatorcontrib>ZOLTAN GYORGYDEAK ; REZSO BOGNAR ; GEZA HORVATH ; ISTVAN KOVACS ; ATTILA JAKAB ; TEREZIA MILE ; ILDIKO MIHOK ; MARIANN FEKETE ; JANOS BALINT ; JUDIT KRUSPER ; FERENC PUSZTAI ; KAROLY LAPIS ; ANDRAS JENEI ; BELA SZENDE ; SANDOR JANCSO</creatorcontrib><description>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1989</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890719&DB=EPODOC&CC=GB&NR=2177089B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890719&DB=EPODOC&CC=GB&NR=2177089B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZOLTAN GYORGYDEAK</creatorcontrib><creatorcontrib>REZSO BOGNAR</creatorcontrib><creatorcontrib>GEZA HORVATH</creatorcontrib><creatorcontrib>ISTVAN KOVACS</creatorcontrib><creatorcontrib>ATTILA JAKAB</creatorcontrib><creatorcontrib>TEREZIA MILE</creatorcontrib><creatorcontrib>ILDIKO MIHOK</creatorcontrib><creatorcontrib>MARIANN FEKETE</creatorcontrib><creatorcontrib>JANOS BALINT</creatorcontrib><creatorcontrib>JUDIT KRUSPER</creatorcontrib><creatorcontrib>FERENC PUSZTAI</creatorcontrib><creatorcontrib>KAROLY LAPIS</creatorcontrib><creatorcontrib>ANDRAS JENEI</creatorcontrib><creatorcontrib>BELA SZENDE</creatorcontrib><creatorcontrib>SANDOR JANCSO</creatorcontrib><title>THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME</title><description>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1989</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAL8fB0jPL38XTx9HN1dgxy8o-I9PF0VnB09nRRcHEN8gxzDPEMcw1WcPRzUQgI8nd2DQ5WcPMPArJdAxyDPP3cFYIdfV15GFjTEnOKU3mhNDeDvJtriLOHbmpBfnxqcUFicmpeakm8u5ORobm5gYWlkzFhFQAkxiux</recordid><startdate>19890719</startdate><enddate>19890719</enddate><creator>ZOLTAN GYORGYDEAK</creator><creator>REZSO BOGNAR</creator><creator>GEZA HORVATH</creator><creator>ISTVAN KOVACS</creator><creator>ATTILA JAKAB</creator><creator>TEREZIA MILE</creator><creator>ILDIKO MIHOK</creator><creator>MARIANN FEKETE</creator><creator>JANOS BALINT</creator><creator>JUDIT KRUSPER</creator><creator>FERENC PUSZTAI</creator><creator>KAROLY LAPIS</creator><creator>ANDRAS JENEI</creator><creator>BELA SZENDE</creator><creator>SANDOR JANCSO</creator><scope>EVB</scope></search><sort><creationdate>19890719</creationdate><title>THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME</title><author>ZOLTAN GYORGYDEAK ; REZSO BOGNAR ; GEZA HORVATH ; ISTVAN KOVACS ; ATTILA JAKAB ; TEREZIA MILE ; ILDIKO MIHOK ; MARIANN FEKETE ; JANOS BALINT ; JUDIT KRUSPER ; FERENC PUSZTAI ; KAROLY LAPIS ; ANDRAS JENEI ; BELA SZENDE ; SANDOR JANCSO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GB2177089B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1989</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZOLTAN GYORGYDEAK</creatorcontrib><creatorcontrib>REZSO BOGNAR</creatorcontrib><creatorcontrib>GEZA HORVATH</creatorcontrib><creatorcontrib>ISTVAN KOVACS</creatorcontrib><creatorcontrib>ATTILA JAKAB</creatorcontrib><creatorcontrib>TEREZIA MILE</creatorcontrib><creatorcontrib>ILDIKO MIHOK</creatorcontrib><creatorcontrib>MARIANN FEKETE</creatorcontrib><creatorcontrib>JANOS BALINT</creatorcontrib><creatorcontrib>JUDIT KRUSPER</creatorcontrib><creatorcontrib>FERENC PUSZTAI</creatorcontrib><creatorcontrib>KAROLY LAPIS</creatorcontrib><creatorcontrib>ANDRAS JENEI</creatorcontrib><creatorcontrib>BELA SZENDE</creatorcontrib><creatorcontrib>SANDOR JANCSO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZOLTAN GYORGYDEAK</au><au>REZSO BOGNAR</au><au>GEZA HORVATH</au><au>ISTVAN KOVACS</au><au>ATTILA JAKAB</au><au>TEREZIA MILE</au><au>ILDIKO MIHOK</au><au>MARIANN FEKETE</au><au>JANOS BALINT</au><au>JUDIT KRUSPER</au><au>FERENC PUSZTAI</au><au>KAROLY LAPIS</au><au>ANDRAS JENEI</au><au>BELA SZENDE</au><au>SANDOR JANCSO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME</title><date>1989-07-19</date><risdate>1989</risdate><abstract>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_GB2177089B |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T16%3A30%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZOLTAN%20GYORGYDEAK&rft.date=1989-07-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EGB2177089B%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |