PROCESS FOR THE PREPARATION OF 6-DEMETHYL-6-DEOXY-6-METHYLENE-5-OXYTETRACYCLIN AND THE 11A-CHLORO-DERIVATIVE THEREOF
The invention relates to a new and improved process for the preparation of 6-demethyl-6-deoxy-6-methylene-5-oxytetracycline and the 11a-chloro derivative thereof by dehydrating 11a-chloro-5-oxytetracycline-6,12-hemiketal, which comprises treating 11a-chloro-5-oxytetracycline-6,12-hemiketal or an aci...
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