PROCEDE ESSENTIELLEMENT AUTOMATISE DE CRIBLAGE A GRANDE ECHELLE DE CELLULES SECRETANT DES ANTICORPS MONOCLONAUX
An automated method for in vitro, large-scale screening of cells (A) that secrete at least one monoclonal antibody (MAb), with specific affinity for a compound of interest (I), is new. Automated method for in vitro, large-scale screening of cells (A) that secrete at least one monoclonal antibody (MA...
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| creator | LECHUGA MARC ROSETO ALBERTO KADOUCHE JEAN |
| description | An automated method for in vitro, large-scale screening of cells (A) that secrete at least one monoclonal antibody (MAb), with specific affinity for a compound of interest (I), is new. Automated method for in vitro, large-scale screening of cells (A) that secrete at least one monoclonal antibody (MAb), with specific affinity for a compound of interest (I) comprises: (a) distributing (A) in the wells of at least one culture plate; (b) culturing the cells, while monitoring their growth and culture quality; (c) iterative screening of (A) for secretion of MAb and cloning of cells that secrete at least one MAb; and (d) selecting at least one (A) that secretes MAb. An independent claim is also included for methods of improving production, by an animal, of cells that produce antibodes against (I). |
| format | Patent |
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Automated method for in vitro, large-scale screening of cells (A) that secrete at least one monoclonal antibody (MAb), with specific affinity for a compound of interest (I) comprises: (a) distributing (A) in the wells of at least one culture plate; (b) culturing the cells, while monitoring their growth and culture quality; (c) iterative screening of (A) for secretion of MAb and cloning of cells that secrete at least one MAb; and (d) selecting at least one (A) that secretes MAb. 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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | PROCEDE ESSENTIELLEMENT AUTOMATISE DE CRIBLAGE A GRANDE ECHELLE DE CELLULES SECRETANT DES ANTICORPS MONOCLONAUX |
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