COMPOSITIONS PHARMACEUTIQUES TRANSDERMIQUES MULTICOUCHES AYANT UN EFFET PROLONGE ET PROCEDE POUR LES PREPARER

COMPOSITIONS PHARMACEUTIQUES TRANSDERMIQUES MULTICOUCHES AYANT UN EFFET PROLONGE ET PROCEDE POUR LES PREPARER

The invention relates to a transdermal laminated pharmaceutical composition (plaster) having prolonged effect, wherein one or more storing layer(s) comprising the active ingredient, an ethylene/vinyl acetate copolymer regulating layer and an adhesive layer are applied onto the carrier. The pharmaceu...

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Hauptverfasser: LASZLO PALLOS, IREN BARTA, LAJOS MAHR, PAL FEKETE, GABOR KOVACS
Format: Patent
Sprache:fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator LASZLO PALLOS
IREN BARTA
LAJOS MAHR
PAL FEKETE
GABOR KOVACS
description The invention relates to a transdermal laminated pharmaceutical composition (plaster) having prolonged effect, wherein one or more storing layer(s) comprising the active ingredient, an ethylene/vinyl acetate copolymer regulating layer and an adhesive layer are applied onto the carrier. The pharmaceutical composition is prepared by coupling a carrier comprising the active ingredient with a regulating layer consisting of an ethylene/vinyl acetate copolymer foil having a vinal acetate content of 2-40 molar %. The foil is previously irradiated in a thickness of 100-300 mu m with a high-energy irradiation in a dose of 1-15 Mrad-preferably with electrone radiation-and thereafter stretched at 80 DEG -90 DEG C. to a thickness of 2-200 mu m. The system comprising the carrier and the regulating layer is subsequently coupled with an adhesive layer.
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The pharmaceutical composition is prepared by coupling a carrier comprising the active ingredient with a regulating layer consisting of an ethylene/vinyl acetate copolymer foil having a vinal acetate content of 2-40 molar %. The foil is previously irradiated in a thickness of 100-300 mu m with a high-energy irradiation in a dose of 1-15 Mrad-preferably with electrone radiation-and thereafter stretched at 80 DEG -90 DEG C. to a thickness of 2-200 mu m. The system comprising the carrier and the regulating layer is subsequently coupled with an adhesive layer.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITIONS PHARMACEUTIQUES TRANSDERMIQUES MULTICOUCHES AYANT UN EFFET PROLONGE ET PROCEDE POUR LES PREPARER
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