VARIANTS DE L'ALPHA-ANTITRYSPINE HUMAINE GLYCOSYLEE ET PROCEDE POUR LA PREPARATION

LA PRESENTE INVENTION CONCERNE UN VECTEUR VIRAL D'EXPRESSION DE L'ALPHA-AT OU D'UN VARIANT DE L'ALPHA-AT CHOISI PARMI : AA ALPHA-AT, AA ALPHA-AT AA, AA ALPHA-AT ET LES VARIANTS CORRESPONDANTS DE LA FORME TRONQUEE DELTA 1 5 ALPHA-AT AINSI QUE DELTA 1 5 ALPHA-AT, CARACTERISE EN CE...

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1. Verfasser: TIM SKFRN, SOPHIE JALLAT ET MICHAEL COURTNEY
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description LA PRESENTE INVENTION CONCERNE UN VECTEUR VIRAL D'EXPRESSION DE L'ALPHA-AT OU D'UN VARIANT DE L'ALPHA-AT CHOISI PARMI : AA ALPHA-AT, AA ALPHA-AT AA, AA ALPHA-AT ET LES VARIANTS CORRESPONDANTS DE LA FORME TRONQUEE DELTA 1 5 ALPHA-AT AINSI QUE DELTA 1 5 ALPHA-AT, CARACTERISE EN CE QU'IL EST CONSTITUE D'UN VIRUS HYBRIDE DE LA VACCINE QUI COMPORTE UNE SEQUENCE D'ADN CODANT POUR LEDIT VARIANT DE L'ALPHA-AT INSERE DANS UNE PARTIE NON ESSENTIELLE DU GENOME DU VIRUS ET SOUS LE CONTROLE D'UNE SEQUENCE D'EXPRESSION EFFICACE DANS LA VACCINE. A viral expression vector of alpha1-AT or of a variant of alpha1-AT, chosen from: [AA ]alpha1-AT, [AA ]alpha1-AT[AA ,AA ]alpha1-AT and the corresponding variants of the truncated form [delta 1->5]alpha1-AT and [delta 1->5]alpha1-AT, characterised in that it consists of a hybrid virus of the vaccine which contains a DNA sequence coding for the said variant of alpha1-AT inserted into a nonessential part of the virus genome and under the control of an expression sequence which is effective in the vaccine.
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A viral expression vector of alpha1-AT or of a variant of alpha1-AT, chosen from: [AA ]alpha1-AT, [AA ]alpha1-AT[AA ,AA ]alpha1-AT and the corresponding variants of the truncated form [delta 1-&gt;5]alpha1-AT and [delta 1-&gt;5]alpha1-AT, characterised in that it consists of a hybrid virus of the vaccine which contains a DNA sequence coding for the said variant of alpha1-AT inserted into a nonessential part of the virus genome and under the control of an expression sequence which is effective in the vaccine.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title VARIANTS DE L'ALPHA-ANTITRYSPINE HUMAINE GLYCOSYLEE ET PROCEDE POUR LA PREPARATION
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