ANTICORPS MONOCLONAUX ANTI-LEISHMANIA, HYBRIDOMES SECRETEURS DE CES ANTICORPS, ANTIGENES DE LEISHMANIA RECONNUS PAR CES ANTICORPS, PROCEDE D'OBTENTION ET APPLICATIONS DE CES ANTICORPS MONOCLONAUX ET DE CES ANTIGENES
The invention relates to hybridomas that produce anti-Leishmania monoclonal antibodies which are characterised by their capacity to inhibit the infection of sarcomatous cells by the promastigote forms of one or more Leishmania species when these sarcomatous cells are brought into contact with the af...
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Zusammenfassung: | The invention relates to hybridomas that produce anti-Leishmania monoclonal antibodies which are characterised by their capacity to inhibit the infection of sarcomatous cells by the promastigote forms of one or more Leishmania species when these sarcomatous cells are brought into contact with the aforementioned promastigote forms preincubated with these monoclonal antibodies under conditions which, in the absence of the aforementioned monoclonal antibodies, would lead to a high level of parasitaemia in the aforementioned cells. These monoclonal antibodies and the parasite proteins they recognise may be employed in operations for the detection of Leishmaniases. |
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