Kemiallisia yhdisteitä

PCT No. PCT/EP93/01520 Sec. 371 Date Nov. 25, 1994 Sec. 102(e) Date Nov. 25, 1994 PCT Filed Jun. 14, 1993 PCT Pub. No. WO93/25548 PCT Pub. Date Dec. 23, 1993This invention relates to heterocyclic compounds which are inhibitors of the enzyme aromatase, to processes for their preparation, to pharmaceu...

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Hauptverfasser:	MERRITT, ANDREW THOMAS, CHERRY, PETER CLIVE, FOXTON, MICHAEL WALTER
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Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator	MERRITT, ANDREW THOMAS CHERRY, PETER CLIVE FOXTON, MICHAEL WALTER
description	PCT No. PCT/EP93/01520 Sec. 371 Date Nov. 25, 1994 Sec. 102(e) Date Nov. 25, 1994 PCT Filed Jun. 14, 1993 PCT Pub. No. WO93/25548 PCT Pub. Date Dec. 23, 1993This invention relates to heterocyclic compounds which are inhibitors of the enzyme aromatase, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine. Particular compounds of the invention are compounds of formula (I) (I) wherein R1 represents a cyano or nitro group; R2 represents hydrogen or one or more halogen atoms; R3 represents a C1-6alkyl group and R4 represents hydrogen or a C1-6alkyl group or R3 and R4 together represent a C3-6cycloalkyl group; and R5 represents hydrogen or one or more halogen atoms or C1-6alkoxy groups and pharmaceutically acceptable salts and solvates thereof.
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Date Dec. 23, 1993This invention relates to heterocyclic compounds which are inhibitors of the enzyme aromatase, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine. Particular compounds of the invention are compounds of formula (I) (I) wherein R1 represents a cyano or nitro group; R2 represents hydrogen or one or more halogen atoms; R3 represents a C1-6alkyl group and R4 represents hydrogen or a C1-6alkyl group or R3 and R4 together represent a C3-6cycloalkyl group; and R5 represents hydrogen or one or more halogen atoms or C1-6alkoxy groups and pharmaceutically acceptable salts and solvates thereof.</description><edition>5</edition><language>fin ; swe</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941215&DB=EPODOC&CC=FI&NR=945907A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941215&DB=EPODOC&CC=FI&NR=945907A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MERRITT, ANDREW THOMAS</creatorcontrib><creatorcontrib>CHERRY, PETER CLIVE</creatorcontrib><creatorcontrib>FOXTON, MICHAEL WALTER</creatorcontrib><title>Kemiallisia yhdisteitä</title><description>PCT No. PCT/EP93/01520 Sec. 371 Date Nov. 25, 1994 Sec. 102(e) Date Nov. 25, 1994 PCT Filed Jun. 14, 1993 PCT Pub. 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Particular compounds of the invention are compounds of formula (I) (I) wherein R1 represents a cyano or nitro group; R2 represents hydrogen or one or more halogen atoms; R3 represents a C1-6alkyl group and R4 represents hydrogen or a C1-6alkyl group or R3 and R4 together represent a C3-6cycloalkyl group; and R5 represents hydrogen or one or more halogen atoms or C1-6alkoxy groups and pharmaceutically acceptable salts and solvates thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD3Ts3NTMzJySzOTFSozEjJLC5JzSw5vISHgTUtMac4lRdKczPIubmGOHvophbkx6cWFyQmp-allsS7eVqamFoamDsaE1QAAFa-IZs</recordid><startdate>19941215</startdate><enddate>19941215</enddate><creator>MERRITT, ANDREW THOMAS</creator><creator>CHERRY, PETER CLIVE</creator><creator>FOXTON, MICHAEL WALTER</creator><scope>EVB</scope></search><sort><creationdate>19941215</creationdate><title>Kemiallisia yhdisteitä</title><author>MERRITT, ANDREW THOMAS ; CHERRY, PETER CLIVE ; FOXTON, MICHAEL WALTER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI945907A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fin ; swe</language><creationdate>1994</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>MERRITT, ANDREW THOMAS</creatorcontrib><creatorcontrib>CHERRY, PETER CLIVE</creatorcontrib><creatorcontrib>FOXTON, MICHAEL WALTER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MERRITT, ANDREW THOMAS</au><au>CHERRY, PETER CLIVE</au><au>FOXTON, MICHAEL WALTER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Kemiallisia yhdisteitä</title><date>1994-12-15</date><risdate>1994</risdate><abstract>PCT No. PCT/EP93/01520 Sec. 371 Date Nov. 25, 1994 Sec. 102(e) Date Nov. 25, 1994 PCT Filed Jun. 14, 1993 PCT Pub. No. WO93/25548 PCT Pub. Date Dec. 23, 1993This invention relates to heterocyclic compounds which are inhibitors of the enzyme aromatase, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine. Particular compounds of the invention are compounds of formula (I) (I) wherein R1 represents a cyano or nitro group; R2 represents hydrogen or one or more halogen atoms; R3 represents a C1-6alkyl group and R4 represents hydrogen or a C1-6alkyl group or R3 and R4 together represent a C3-6cycloalkyl group; and R5 represents hydrogen or one or more halogen atoms or C1-6alkoxy groups and pharmaceutically acceptable salts and solvates thereof.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title	Kemiallisia yhdisteitä
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