FOERFARANDE FOER FRAMSTAELLNING AV 4(5)-SUBSTITUERADE IMIDAZOLDERIVAT

The invention relates to a process for the preparation of 4/5/-substituted imidazole derivatives I wherein R1 is alkyl, OH substituted alkyl or alkenyl R3 is H, CH3, CH2CH3, OCH3 or Hal R4 is H, CH3, CH2CH3, OCH3 or Hal and Hal is halogen and the non-toxic acid addition salts thereof. The compounds...

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Hauptverfasser: KARJALAINEN, ARJA LEENA, KARJALAINEN, ARTO JOHANNES
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creator KARJALAINEN, ARJA LEENA
KARJALAINEN, ARTO JOHANNES
description The invention relates to a process for the preparation of 4/5/-substituted imidazole derivatives I wherein R1 is alkyl, OH substituted alkyl or alkenyl R3 is H, CH3, CH2CH3, OCH3 or Hal R4 is H, CH3, CH2CH3, OCH3 or Hal and Hal is halogen and the non-toxic acid addition salts thereof. The compounds and their salts possess valuable pharmacological properties and are useful especially as selective α2 -receptor antagonists.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FOERFARANDE FOER FRAMSTAELLNING AV 4(5)-SUBSTITUERADE IMIDAZOLDERIVAT
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