TIAZOLIN-4(S) -KARBOXYLSYRADERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING
The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl o...
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| creator | KOVACS, ISTVAN JANCSO, SANDOR MILE, TEREZIA BALINT, JANOS FEKETE(HUSZKA), MARIANN BOGNAR, REZSO JENEI, ANDRAS LAPIS, KAROLY PUSZTAI, FERENC JAKAB, ATTILA SZENDE, BELA HORVATH, GEZA KRUSPER(HAM), JUDIT MIHOK(BORBELY), ILDIKO GYOERGYDEAK, ZOLTAN |
| description | The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin. |
| format | Patent |
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Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><edition>4</edition><language>fin</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860618&DB=EPODOC&CC=FI&NR=862608A0$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860618&DB=EPODOC&CC=FI&NR=862608A0$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KOVACS, ISTVAN</creatorcontrib><creatorcontrib>JANCSO, SANDOR</creatorcontrib><creatorcontrib>MILE, TEREZIA</creatorcontrib><creatorcontrib>BALINT, JANOS</creatorcontrib><creatorcontrib>FEKETE(HUSZKA), MARIANN</creatorcontrib><creatorcontrib>BOGNAR, REZSO</creatorcontrib><creatorcontrib>JENEI, ANDRAS</creatorcontrib><creatorcontrib>LAPIS, KAROLY</creatorcontrib><creatorcontrib>PUSZTAI, FERENC</creatorcontrib><creatorcontrib>JAKAB, ATTILA</creatorcontrib><creatorcontrib>SZENDE, BELA</creatorcontrib><creatorcontrib>HORVATH, GEZA</creatorcontrib><creatorcontrib>KRUSPER(HAM), JUDIT</creatorcontrib><creatorcontrib>MIHOK(BORBELY), ILDIKO</creatorcontrib><creatorcontrib>GYOERGYDEAK, ZOLTAN</creatorcontrib><title>TIAZOLIN-4(S) -KARBOXYLSYRADERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING</title><description>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1986</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAJ8XSM8vfx9NM10QjWVND1dgxy8o-I9AmODHJ0cQ3yDHMMUfB39lBw83cNcnMMcvRzcQWzFYCSjsEKbkGOvsEhjq4-Pn6efu48DKxpiTnFqbxQmptB3s01xNlDN7UgPz61uCAxOTUvtSTezdPCzMjMwMLRwJiwCgAHFi0m</recordid><startdate>19860618</startdate><enddate>19860618</enddate><creator>KOVACS, ISTVAN</creator><creator>JANCSO, SANDOR</creator><creator>MILE, TEREZIA</creator><creator>BALINT, JANOS</creator><creator>FEKETE(HUSZKA), MARIANN</creator><creator>BOGNAR, REZSO</creator><creator>JENEI, ANDRAS</creator><creator>LAPIS, KAROLY</creator><creator>PUSZTAI, FERENC</creator><creator>JAKAB, ATTILA</creator><creator>SZENDE, BELA</creator><creator>HORVATH, GEZA</creator><creator>KRUSPER(HAM), JUDIT</creator><creator>MIHOK(BORBELY), ILDIKO</creator><creator>GYOERGYDEAK, ZOLTAN</creator><scope>EVB</scope></search><sort><creationdate>19860618</creationdate><title>TIAZOLIN-4(S) -KARBOXYLSYRADERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING</title><author>KOVACS, ISTVAN ; JANCSO, SANDOR ; MILE, TEREZIA ; BALINT, JANOS ; FEKETE(HUSZKA), MARIANN ; BOGNAR, REZSO ; JENEI, ANDRAS ; LAPIS, KAROLY ; PUSZTAI, FERENC ; JAKAB, ATTILA ; SZENDE, BELA ; HORVATH, GEZA ; KRUSPER(HAM), JUDIT ; MIHOK(BORBELY), ILDIKO ; GYOERGYDEAK, ZOLTAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI862608A03</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fin</language><creationdate>1986</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KOVACS, ISTVAN</creatorcontrib><creatorcontrib>JANCSO, SANDOR</creatorcontrib><creatorcontrib>MILE, TEREZIA</creatorcontrib><creatorcontrib>BALINT, JANOS</creatorcontrib><creatorcontrib>FEKETE(HUSZKA), MARIANN</creatorcontrib><creatorcontrib>BOGNAR, REZSO</creatorcontrib><creatorcontrib>JENEI, ANDRAS</creatorcontrib><creatorcontrib>LAPIS, KAROLY</creatorcontrib><creatorcontrib>PUSZTAI, FERENC</creatorcontrib><creatorcontrib>JAKAB, ATTILA</creatorcontrib><creatorcontrib>SZENDE, BELA</creatorcontrib><creatorcontrib>HORVATH, GEZA</creatorcontrib><creatorcontrib>KRUSPER(HAM), JUDIT</creatorcontrib><creatorcontrib>MIHOK(BORBELY), ILDIKO</creatorcontrib><creatorcontrib>GYOERGYDEAK, ZOLTAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KOVACS, ISTVAN</au><au>JANCSO, SANDOR</au><au>MILE, TEREZIA</au><au>BALINT, JANOS</au><au>FEKETE(HUSZKA), MARIANN</au><au>BOGNAR, REZSO</au><au>JENEI, ANDRAS</au><au>LAPIS, KAROLY</au><au>PUSZTAI, FERENC</au><au>JAKAB, ATTILA</au><au>SZENDE, BELA</au><au>HORVATH, GEZA</au><au>KRUSPER(HAM), JUDIT</au><au>MIHOK(BORBELY), ILDIKO</au><au>GYOERGYDEAK, ZOLTAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TIAZOLIN-4(S) -KARBOXYLSYRADERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING</title><date>1986-06-18</date><risdate>1986</risdate><abstract>The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) (I) wherein R1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C1-4 alkyl or C2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group, stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C1-4 alkyl group or aryl group; R3 represents hydrogen or an optionally substituted C1-4 alkyl or acyl group or aryl group as well as their salts. Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations. The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TIAZOLIN-4(S) -KARBOXYLSYRADERIVAT OCH FOERFARANDE FOER DERAS FRAMSTAELLNING |
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