FOERFARANDE FOER FRAMSTAELLNING AV HETEROCYKLISKA FOERENINGAR
The invention relates to a process for the preparation of compounds of general formula (I)whereinR' represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4)alkyl, C3-6 alkenyl, C3-10 alkynyl, phenyl or phenyl-(C1-3)alkyl group, and one of the groups represented by R2...
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| creator | GODFREY, NEIL BELL, JAMES ANGUS HUMBER, DAVID CEDRIC COATES, IAN HAROLD EWAN, GEORGE BLANCH |
| description | The invention relates to a process for the preparation of compounds of general formula (I)whereinR' represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4)alkyl, C3-6 alkenyl, C3-10 alkynyl, phenyl or phenyl-(C1-3)alkyl group, and one of the groups represented by R2, R3 and R4 is a hydrogen atom or a C,.6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl or phenyl-IC1-3)alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C1-6 alkyl group; or a salt or protected derivative thereof by cyclisation of a compound of general formula (ll)wherein X represents a hydrogen atom or a halogen atom and R', R2, R3, and R4 are as defined above, or a salt or a protected derivative thereof.The compounds of formula (I) are potent and selective antagonists at "neuronal" 5-hydroxytryptamine receptors. |
| format | Patent |
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or a salt or protected derivative thereof by cyclisation of a compound of general formula (ll)wherein X represents a hydrogen atom or a halogen atom and R', R2, R3, and R4 are as defined above, or a salt or a protected derivative thereof.The compounds of formula (I) are potent and selective antagonists at "neuronal" 5-hydroxytryptamine receptors.</description><edition>5</edition><language>fin</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1991</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910815&DB=EPODOC&CC=FI&NR=84351B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19910815&DB=EPODOC&CC=FI&NR=84351B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GODFREY, NEIL</creatorcontrib><creatorcontrib>BELL, JAMES ANGUS</creatorcontrib><creatorcontrib>HUMBER, DAVID CEDRIC</creatorcontrib><creatorcontrib>COATES, IAN HAROLD</creatorcontrib><creatorcontrib>EWAN, GEORGE BLANCH</creatorcontrib><title>FOERFARANDE FOER FRAMSTAELLNING AV HETEROCYKLISKA FOERENINGAR</title><description>The invention relates to a process for the preparation of compounds of general formula (I)whereinR' represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4)alkyl, C3-6 alkenyl, C3-10 alkynyl, phenyl or phenyl-(C1-3)alkyl group, and one of the groups represented by R2, R3 and R4 is a hydrogen atom or a C,.6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl or phenyl-IC1-3)alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C1-6 alkyl group; 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BELL, JAMES ANGUS ; HUMBER, DAVID CEDRIC ; COATES, IAN HAROLD ; EWAN, GEORGE BLANCH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI84351BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fin</language><creationdate>1991</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>GODFREY, NEIL</creatorcontrib><creatorcontrib>BELL, JAMES ANGUS</creatorcontrib><creatorcontrib>HUMBER, DAVID CEDRIC</creatorcontrib><creatorcontrib>COATES, IAN HAROLD</creatorcontrib><creatorcontrib>EWAN, GEORGE BLANCH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GODFREY, NEIL</au><au>BELL, JAMES ANGUS</au><au>HUMBER, DAVID CEDRIC</au><au>COATES, IAN HAROLD</au><au>EWAN, GEORGE BLANCH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FOERFARANDE FOER FRAMSTAELLNING AV HETEROCYKLISKA FOERENINGAR</title><date>1991-08-15</date><risdate>1991</risdate><abstract>The invention relates to a process for the preparation of compounds of general formula (I)whereinR' represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4)alkyl, C3-6 alkenyl, C3-10 alkynyl, phenyl or phenyl-(C1-3)alkyl group, and one of the groups represented by R2, R3 and R4 is a hydrogen atom or a C,.6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl or phenyl-IC1-3)alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C1-6 alkyl group; or a salt or protected derivative thereof by cyclisation of a compound of general formula (ll)wherein X represents a hydrogen atom or a halogen atom and R', R2, R3, and R4 are as defined above, or a salt or a protected derivative thereof.The compounds of formula (I) are potent and selective antagonists at "neuronal" 5-hydroxytryptamine receptors.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | FOERFARANDE FOER FRAMSTAELLNING AV HETEROCYKLISKA FOERENINGAR |
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