FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA 1-ALKYL-2-AMINOTETRALINDERIVAT OCH EN VID FOERFARANDET ANVAEND MELLANPRODUKT
Compounds of the formula I wherein R3 and the NR1R2 group are in a cis-position to each other and wherein Y is OH, R4COO, (R5)2NCOO or R6O either in position 5 or position 7, whereby R4 is an alkyl group having 1-5 carbon atoms or a possibly substituted phenyl group, R5 is an alkyl group having 1-5...
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| creator | HACKSELL, ULI ALF NILSSON, JOHAN LARS GUNNAR LINDBERG, PER LENNART HJORT, JOHN STEPHAN MIKAEL ARVIDSSON, FOLKE LARS-ERIK CARLSSON, PER ARVID EMIL JOHANSSON, ANETTE MARGARETA SANCHEZ, DOMINGO WIKSTROEM, HAOKAN VILHELM |
| description | Compounds of the formula I wherein R3 and the NR1R2 group are in a cis-position to each other and wherein Y is OH, R4COO, (R5)2NCOO or R6O either in position 5 or position 7, whereby R4 is an alkyl group having 1-5 carbon atoms or a possibly substituted phenyl group, R5 is an alkyl group having 1-5 carbon atoms and R6 is an allyl or benzyl group, R1 is hydrogen or an alkyl group having 1-3 carbon atoms, R2 is an alkyl group having 1-6 carbon atoms, a phenylalkyl- or m-hydroxyphenylalkyl group with 2-4 carbon atoms in the alkyl part, or an alkenyl group with 3-6 carbon atoms other than 1-alkenyl, and R3 is an alkyl group having 1-3 carbon atoms, processes and intermediates for their preparation, pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system. |
| format | Patent |
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The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.</description><edition>4</edition><language>fin</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1989</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890228&DB=EPODOC&CC=FI&NR=78067B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890228&DB=EPODOC&CC=FI&NR=78067B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HACKSELL, ULI ALF</creatorcontrib><creatorcontrib>NILSSON, JOHAN LARS GUNNAR</creatorcontrib><creatorcontrib>LINDBERG, PER LENNART</creatorcontrib><creatorcontrib>HJORT, JOHN STEPHAN MIKAEL</creatorcontrib><creatorcontrib>ARVIDSSON, FOLKE LARS-ERIK</creatorcontrib><creatorcontrib>CARLSSON, PER ARVID EMIL</creatorcontrib><creatorcontrib>JOHANSSON, ANETTE MARGARETA</creatorcontrib><creatorcontrib>SANCHEZ, DOMINGO</creatorcontrib><creatorcontrib>WIKSTROEM, HAOKAN VILHELM</creatorcontrib><title>FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA 1-ALKYL-2-AMINOTETRALINDERIVAT OCH EN VID FOERFARANDET ANVAEND MELLANPRODUKT</title><description>Compounds of the formula I wherein R3 and the NR1R2 group are in a cis-position to each other and wherein Y is OH, R4COO, (R5)2NCOO or R6O either in position 5 or position 7, whereby R4 is an alkyl group having 1-5 carbon atoms or a possibly substituted phenyl group, R5 is an alkyl group having 1-5 carbon atoms and R6 is an allyl or benzyl group, R1 is hydrogen or an alkyl group having 1-3 carbon atoms, R2 is an alkyl group having 1-6 carbon atoms, a phenylalkyl- or m-hydroxyphenylalkyl group with 2-4 carbon atoms in the alkyl part, or an alkenyl group with 3-6 carbon atoms other than 1-alkenyl, and R3 is an alkyl group having 1-3 carbon atoms, processes and intermediates for their preparation, pharmaceutical preparations and methods of treatment employing such compounds. 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The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA 1-ALKYL-2-AMINOTETRALINDERIVAT OCH EN VID FOERFARANDET ANVAEND MELLANPRODUKT |
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