FOERFARANDE FOER FRAMSTAELLNING AV CEFUROXIM-1-ACETOXIETYLESTER

A process for obtaining highly pure crystalline cefuroxime axetil comprises crystallising cefuroxime axetil from a solution thereof in an organic or aqueous solvent or a mixture thereof and then drying and isolating the product. Preferred solvents are alkyl acetates in admixture with ethers or aliph...

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Hauptverfasser:	CRISP, HAROLD ALFRED, TURNBULL, JOHN PETER, WRIGHT, MICHAEL, OUGHTON, JOHN FRANCIS
Format:	Patent
Sprache:	fin
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	CRISP, HAROLD ALFRED TURNBULL, JOHN PETER WRIGHT, MICHAEL OUGHTON, JOHN FRANCIS
description	A process for obtaining highly pure crystalline cefuroxime axetil comprises crystallising cefuroxime axetil from a solution thereof in an organic or aqueous solvent or a mixture thereof and then drying and isolating the product. Preferred solvents are alkyl acetates in admixture with ethers or aliphatic or aromatic hydrocarbons. The higher the yield from crystallisation, the closer to a 1:1 stoichiometric ratio of R:S isomers the product will contain, this being most desirable for an antibiotic product which is to be administered orally.
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Preferred solvents are alkyl acetates in admixture with ethers or aliphatic or aromatic hydrocarbons. 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Preferred solvents are alkyl acetates in admixture with ethers or aliphatic or aromatic hydrocarbons. The higher the yield from crystallisation, the closer to a 1:1 stoichiometric ratio of R:S isomers the product will contain, this being most desirable for an antibiotic product which is to be administered orally.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	FOERFARANDE FOER FRAMSTAELLNING AV CEFUROXIM-1-ACETOXIETYLESTER
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