FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT AKTIVT PROLINDERIVAT
Proline derivatives of the formula (I): (wherein R is an acyl group bonded to the alpha -amino group of amino acid A and is selected from the group consisting of cyclopropanecarbonyl, cyclohexanecarbonyl and adamantanecarbonyl groups; A is glycine, sarcosine or alpha -D-amino acid residue the carbon...
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| creator | TANAKA, SADAO AONO, JUNICHIRO HATA, SHUN-ICHI MATSUNAGA, ISAO FUKUSHIMA, MASAFUMI SAKAI, KAZUSHIGE KUROMARU, KIYONORI OBATAKE, NORIKO IWAOKA, TOMOYASU NABATA, HIROYUKI NAKANO, HIDEKI HINOHARA, YOSHIKAZU FUJIMURA, YASUO |
| description | Proline derivatives of the formula (I): (wherein R is an acyl group bonded to the alpha -amino group of amino acid A and is selected from the group consisting of cyclopropanecarbonyl, cyclohexanecarbonyl and adamantanecarbonyl groups; A is glycine, sarcosine or alpha -D-amino acid residue the carbonyl group of which forms a thiol ester bond with the sulfur atom) or a pharmaceutically acceptable salt thereof, and a process for producing the same are disclosed. The proline derivatives are useful for treating hypertension due to angiotensin II, and as an agent to treat cardiac insufficiency. |
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The proline derivatives are useful for treating hypertension due to angiotensin II, and as an agent to treat cardiac insufficiency.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY CONVEYING HANDLING THIN OR FILAMENTARY MATERIAL HANDLING THIN OR FILAMENTARY MATERIAL, e.g. SHEETS, WEBS,CABLES HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PACKING PERFORMING OPERATIONS STORING TRANSPORTING |
| title | FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT AKTIVT PROLINDERIVAT |
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