FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA AMIDINODERIVAT

Amidino compounds represented by the formulaand pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful anti- trypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1r, C1s) activities and an anticomplement activity, they...

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Hauptverfasser: OKUTOME, TOSHIYUKI, NAKAYAMA, TOYOO, YAEGASHI, TAKASHI, KURUMI, MASATERU, FUJII, SETSURO
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creator OKUTOME, TOSHIYUKI
NAKAYAMA, TOYOO
YAEGASHI, TAKASHI
KURUMI, MASATERU
FUJII, SETSURO
description Amidino compounds represented by the formulaand pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful anti- trypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1r, C1s) activities and an anticomplement activity, they are also useful as anticomplement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formulawith 6-amidino-2-naphthol and, if necessary, can be transformed into pharmaceutically acceptable acid addition salts thereof.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA AMIDINODERIVAT
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