FOERFARANDE FOER FRAMSTAELLNING AV FARMAKOLOGISKT VERKSAMMA N-XACYKLYL-ALKYL-PIPERIDINER
The invention concerns compounds of the formula I wherein Ph is unsubstituted 1,2-phenylene or 1,2-phenylene substituted by one to three identical or different members selected from lower alkyl, lower alkoxy, lower alkylene-dioxy, halogeno or trifluoromethyl, each of R1 and R2 is hydrogen or lower a...
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| creator | HUEBNER CHARLES FERDINAND |
| description | The invention concerns compounds of the formula I wherein Ph is unsubstituted 1,2-phenylene or 1,2-phenylene substituted by one to three identical or different members selected from lower alkyl, lower alkoxy, lower alkylene-dioxy, halogeno or trifluoromethyl, each of R1 and R2 is hydrogen or lower alkyl, each of R3 and R4 is hydrogen, lower alkyl or (R3 +R4) is Ph or lower alkylene separating both nitrogens by 2 to 4 carbon atoms, R5 is hydrogen, lower alkyl or HPh, X is oxo, thioxo, imino or lower alkylimino, Y is epoxy, epithio or sulfinyl, m is an integerfrom 1 to 7, each of p and q is an integer from 1 to 3, but (p+q)=4, and acid additional salts thereof. The compounds exhibit stimulant and antidepressive effects. They are prepared by reduction of corresponding amides. |
| format | Patent |
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The compounds exhibit stimulant and antidepressive effects. They are prepared by reduction of corresponding amides.</description><edition>3</edition><language>fin</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1984</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19841010&DB=EPODOC&CC=FI&NR=66373C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19841010&DB=EPODOC&CC=FI&NR=66373C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HUEBNER CHARLES FERDINAND</creatorcontrib><title>FOERFARANDE FOER FRAMSTAELLNING AV FARMAKOLOGISKT VERKSAMMA N-XACYKLYL-ALKYL-PIPERIDINER</title><description>The invention concerns compounds of the formula I wherein Ph is unsubstituted 1,2-phenylene or 1,2-phenylene substituted by one to three identical or different members selected from lower alkyl, lower alkoxy, lower alkylene-dioxy, halogeno or trifluoromethyl, each of R1 and R2 is hydrogen or lower alkyl, each of R3 and R4 is hydrogen, lower alkyl or (R3 +R4) is Ph or lower alkylene separating both nitrogens by 2 to 4 carbon atoms, R5 is hydrogen, lower alkyl or HPh, X is oxo, thioxo, imino or lower alkylimino, Y is epoxy, epithio or sulfinyl, m is an integerfrom 1 to 7, each of p and q is an integer from 1 to 3, but (p+q)=4, and acid additional salts thereof. The compounds exhibit stimulant and antidepressive effects. They are prepared by reduction of corresponding amides.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1984</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFir0KwjAURrs4iPoKkhfIFKjzJb2pl_yVm1DaqRSJk2ihvj9WcHf5zoHz7avBRGQDDKFB8XVhGHzKgM4FCq2AXmzZg40utpRsFj2yTeA9iCAH0KN1o5Pg7LYddcjUUEA-Vrv7_FjL6cdDdTaY9VWW5TWVdZlv5Vnek6G6Vheltfp7-AAOBjCr</recordid><startdate>19841010</startdate><enddate>19841010</enddate><creator>HUEBNER CHARLES FERDINAND</creator><scope>EVB</scope></search><sort><creationdate>19841010</creationdate><title>FOERFARANDE FOER FRAMSTAELLNING AV FARMAKOLOGISKT VERKSAMMA N-XACYKLYL-ALKYL-PIPERIDINER</title><author>HUEBNER CHARLES FERDINAND</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI66373CC3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fin</language><creationdate>1984</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HUEBNER CHARLES FERDINAND</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HUEBNER CHARLES FERDINAND</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FOERFARANDE FOER FRAMSTAELLNING AV FARMAKOLOGISKT VERKSAMMA N-XACYKLYL-ALKYL-PIPERIDINER</title><date>1984-10-10</date><risdate>1984</risdate><abstract>The invention concerns compounds of the formula I wherein Ph is unsubstituted 1,2-phenylene or 1,2-phenylene substituted by one to three identical or different members selected from lower alkyl, lower alkoxy, lower alkylene-dioxy, halogeno or trifluoromethyl, each of R1 and R2 is hydrogen or lower alkyl, each of R3 and R4 is hydrogen, lower alkyl or (R3 +R4) is Ph or lower alkylene separating both nitrogens by 2 to 4 carbon atoms, R5 is hydrogen, lower alkyl or HPh, X is oxo, thioxo, imino or lower alkylimino, Y is epoxy, epithio or sulfinyl, m is an integerfrom 1 to 7, each of p and q is an integer from 1 to 3, but (p+q)=4, and acid additional salts thereof. The compounds exhibit stimulant and antidepressive effects. They are prepared by reduction of corresponding amides.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | FOERFARANDE FOER FRAMSTAELLNING AV FARMAKOLOGISKT VERKSAMMA N-XACYKLYL-ALKYL-PIPERIDINER |
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