PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE
The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fin |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LEE, Jung-Ae LEE, Jun-Sup LIM, Jong-Chul SHIN, Woo-Seob OH, Sang-Ho JU, Hyun KHOO, Ja-Heouk JEON, Sang-Seol LEE, Doo-Byung |
| description | The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_FI3658547TT3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>FI3658547TT3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_FI3658547TT33</originalsourceid><addsrcrecordid>eNqNTLsKwjAU7eIg6j_UrR3uoGnVNbSpCTS54TaDcSlF4iRa0NV_Nz4-QDhwnpxp8rSElei6tEFKLQnLSZl9aiArISveiIX2LTCwUpgoVhKsJ37EKMG3eTRKq1oZWEfLtTKYQwFaOIkHH0ONZCW2Mf8-5Lyiz7AW82RyHi73sPjxLFk2wlUSwnjrw30cTuEaHn2j2KbclcXWOcb-2bwAR3Y7Pg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE</title><source>esp@cenet</source><creator>LEE, Jung-Ae ; LEE, Jun-Sup ; LIM, Jong-Chul ; SHIN, Woo-Seob ; OH, Sang-Ho ; JU, Hyun ; KHOO, Ja-Heouk ; JEON, Sang-Seol ; LEE, Doo-Byung</creator><creatorcontrib>LEE, Jung-Ae ; LEE, Jun-Sup ; LIM, Jong-Chul ; SHIN, Woo-Seob ; OH, Sang-Ho ; JU, Hyun ; KHOO, Ja-Heouk ; JEON, Sang-Seol ; LEE, Doo-Byung</creatorcontrib><description>The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.</description><language>eng ; fin</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231026&DB=EPODOC&CC=FI&NR=3658547T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231026&DB=EPODOC&CC=FI&NR=3658547T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE, Jung-Ae</creatorcontrib><creatorcontrib>LEE, Jun-Sup</creatorcontrib><creatorcontrib>LIM, Jong-Chul</creatorcontrib><creatorcontrib>SHIN, Woo-Seob</creatorcontrib><creatorcontrib>OH, Sang-Ho</creatorcontrib><creatorcontrib>JU, Hyun</creatorcontrib><creatorcontrib>KHOO, Ja-Heouk</creatorcontrib><creatorcontrib>JEON, Sang-Seol</creatorcontrib><creatorcontrib>LEE, Doo-Byung</creatorcontrib><title>PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE</title><description>The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTLsKwjAU7eIg6j_UrR3uoGnVNbSpCTS54TaDcSlF4iRa0NV_Nz4-QDhwnpxp8rSElei6tEFKLQnLSZl9aiArISveiIX2LTCwUpgoVhKsJ37EKMG3eTRKq1oZWEfLtTKYQwFaOIkHH0ONZCW2Mf8-5Lyiz7AW82RyHi73sPjxLFk2wlUSwnjrw30cTuEaHn2j2KbclcXWOcb-2bwAR3Y7Pg</recordid><startdate>20231026</startdate><enddate>20231026</enddate><creator>LEE, Jung-Ae</creator><creator>LEE, Jun-Sup</creator><creator>LIM, Jong-Chul</creator><creator>SHIN, Woo-Seob</creator><creator>OH, Sang-Ho</creator><creator>JU, Hyun</creator><creator>KHOO, Ja-Heouk</creator><creator>JEON, Sang-Seol</creator><creator>LEE, Doo-Byung</creator><scope>EVB</scope></search><sort><creationdate>20231026</creationdate><title>PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE</title><author>LEE, Jung-Ae ; LEE, Jun-Sup ; LIM, Jong-Chul ; SHIN, Woo-Seob ; OH, Sang-Ho ; JU, Hyun ; KHOO, Ja-Heouk ; JEON, Sang-Seol ; LEE, Doo-Byung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI3658547TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fin</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE, Jung-Ae</creatorcontrib><creatorcontrib>LEE, Jun-Sup</creatorcontrib><creatorcontrib>LIM, Jong-Chul</creatorcontrib><creatorcontrib>SHIN, Woo-Seob</creatorcontrib><creatorcontrib>OH, Sang-Ho</creatorcontrib><creatorcontrib>JU, Hyun</creatorcontrib><creatorcontrib>KHOO, Ja-Heouk</creatorcontrib><creatorcontrib>JEON, Sang-Seol</creatorcontrib><creatorcontrib>LEE, Doo-Byung</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE, Jung-Ae</au><au>LEE, Jun-Sup</au><au>LIM, Jong-Chul</au><au>SHIN, Woo-Seob</au><au>OH, Sang-Ho</au><au>JU, Hyun</au><au>KHOO, Ja-Heouk</au><au>JEON, Sang-Seol</au><au>LEE, Doo-Byung</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE</title><date>2023-10-26</date><risdate>2023</risdate><abstract>The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fin |
| recordid | cdi_epo_espacenet_FI3658547TT3 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARING N-(5-(4-(4-FORMYL-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YLAMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T08%3A35%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LEE,%20Jung-Ae&rft.date=2023-10-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EFI3658547TT3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |