PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER
The present invention provides MDM2 inhibitor compounds of Formula IE,which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
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| creator | Gustin, Darin James Yan, Xuelei McGee, Lawrence R McMinn, Dustin Gribble, Jr Zhu, Jiang Chen, Xiaoqi Heath, Julie Anne Li, Zhihong Mihalic, Jeffrey Thomas Beck, Hilary Place Jiao, Xianjun Fu, Zice Deignan, Jeffrey Ma, Zhihua Wang, Xiaodong Huang, Xin Lai, Sujen Eksterowicz, John Roveto, Philip Marley Yu, Ming Kayser, Frank Kopecky, David John Gonzalez Lopez de Turiso, Felix McIntosh, Joel Connors, Richard Victor Olson, Steven Howard Gonzalez Buenrostro, Ana Fu, Jiasheng Liu, Jiwen Low, Jonathan Dante Li, Yihong Duquette, Jason A Fox, Brian Matthew Bartberger, Michael David Sun, Daqing Wang, Yingcai Medina, Julio Cesar Fisher, Benjamin Johnson, Michael Lucas, Brian Stuart Rew, Yosup |
| description | The present invention provides MDM2 inhibitor compounds of Formula IE,which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor. |
| format | Patent |
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The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER |
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