Menetelmä epoksidin valmistamiseksi

A process for synthesizing the epoxide of formula (I) consists of, at a minimum, formation of a halohydrin form the allyl acetonide reactant, followed by base-induced cyclization, the epoxide product (I) being useful as an intermediate for the synthesis of inhibitors of renin or HIV protease or othe...

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Hauptverfasser: MALIGRES, PETER E, UPADHYAY, VEENA, ASKIN, DAVID, VOLANTE, RALPH P, ROSSEN, KAI, REIDER, PAUL J, ENG, KAN K
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creator MALIGRES, PETER E
UPADHYAY, VEENA
ASKIN, DAVID
VOLANTE, RALPH P
ROSSEN, KAI
REIDER, PAUL J
ENG, KAN K
description A process for synthesizing the epoxide of formula (I) consists of, at a minimum, formation of a halohydrin form the allyl acetonide reactant, followed by base-induced cyclization, the epoxide product (I) being useful as an intermediate for the synthesis of inhibitors of renin or HIV protease or other proteases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Menetelmä epoksidin valmistamiseksi
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