Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi
This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula wherein -YR1 is one substituent on the 5, 6, 7 or 8 position of the aromatic ring, and is -S(C1-C3)alkyl or OR1 wherein R1 is selected from the group consisting of (C1-C8) al...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | fin ; swe |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SVENSSON, KJELL ANDERS IVAN CARLSSON, PER ARVID EMIL WIKSTROEM, HAAKAN VILHELM ANDERSSON, BENGT RONNY |
| description | This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula wherein -YR1 is one substituent on the 5, 6, 7 or 8 position of the aromatic ring, and is -S(C1-C3)alkyl or OR1 wherein R1 is selected from the group consisting of (C1-C8) alkyl, (C1-C8) alkenyl,- CH2-(C3-C8) cycloalkyl or benzyl; wherein R2 is hydrogen or (C1-C3) alkyl; wherein R3 is -CH2-(C3-C8) cycloalkyl; wherein R4 is hydrogen, (C1-C8) alkyl, -CH2-(C3-C4) cycloalkyl -(CH2)m-R5 or -CH2-CH2-X-(CH2)nCH3; wherein n is zero to 3 and m is 2 or 3; wherein X is oxygen or sulfur; and wherein R5 is phenyl; phenyl substituted with one or two substituent groups selected from chlorine, bromine, fluorine, (C1-C3)alkoxy or (C1-C3)alkyl; 2-thiophene; or 3-thiophene; with the proviso that when R3 contains more than four carbon atoms and R4 is alkyl said alkyl contains from one to 3 carbon atoms. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_FI102893BB1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>FI102893BB1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_FI102893BB13</originalsourceid><addsrcrecordid>eNrjZIjxTc1LLUnNyT28RKEktSixILW0pCSzOLW4JFMh-_CSypKSw9uyU3MK8jOLS1LzFIx0E3Mz8_JLUkuKEnMyM_Mys_IzUhLz8hIh0mWJOblAFlBNcWp2cSYPA2taYk5xKi-U5mZQcHMNcfbQTS3Ij08tLkhMBlke7-ZpaGBkYWns5GRoTIQSAJlNP84</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi</title><source>esp@cenet</source><creator>SVENSSON, KJELL ANDERS IVAN ; CARLSSON, PER ARVID EMIL ; WIKSTROEM, HAAKAN VILHELM ; ANDERSSON, BENGT RONNY</creator><creatorcontrib>SVENSSON, KJELL ANDERS IVAN ; CARLSSON, PER ARVID EMIL ; WIKSTROEM, HAAKAN VILHELM ; ANDERSSON, BENGT RONNY</creatorcontrib><description>This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula wherein -YR1 is one substituent on the 5, 6, 7 or 8 position of the aromatic ring, and is -S(C1-C3)alkyl or OR1 wherein R1 is selected from the group consisting of (C1-C8) alkyl, (C1-C8) alkenyl,- CH2-(C3-C8) cycloalkyl or benzyl; wherein R2 is hydrogen or (C1-C3) alkyl; wherein R3 is -CH2-(C3-C8) cycloalkyl; wherein R4 is hydrogen, (C1-C8) alkyl, -CH2-(C3-C4) cycloalkyl -(CH2)m-R5 or -CH2-CH2-X-(CH2)nCH3; wherein n is zero to 3 and m is 2 or 3; wherein X is oxygen or sulfur; and wherein R5 is phenyl; phenyl substituted with one or two substituent groups selected from chlorine, bromine, fluorine, (C1-C3)alkoxy or (C1-C3)alkyl; 2-thiophene; or 3-thiophene; with the proviso that when R3 contains more than four carbon atoms and R4 is alkyl said alkyl contains from one to 3 carbon atoms.</description><edition>6</edition><language>fin ; swe</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990315&DB=EPODOC&CC=FI&NR=102893B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990315&DB=EPODOC&CC=FI&NR=102893B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SVENSSON, KJELL ANDERS IVAN</creatorcontrib><creatorcontrib>CARLSSON, PER ARVID EMIL</creatorcontrib><creatorcontrib>WIKSTROEM, HAAKAN VILHELM</creatorcontrib><creatorcontrib>ANDERSSON, BENGT RONNY</creatorcontrib><title>Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi</title><description>This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula wherein -YR1 is one substituent on the 5, 6, 7 or 8 position of the aromatic ring, and is -S(C1-C3)alkyl or OR1 wherein R1 is selected from the group consisting of (C1-C8) alkyl, (C1-C8) alkenyl,- CH2-(C3-C8) cycloalkyl or benzyl; wherein R2 is hydrogen or (C1-C3) alkyl; wherein R3 is -CH2-(C3-C8) cycloalkyl; wherein R4 is hydrogen, (C1-C8) alkyl, -CH2-(C3-C4) cycloalkyl -(CH2)m-R5 or -CH2-CH2-X-(CH2)nCH3; wherein n is zero to 3 and m is 2 or 3; wherein X is oxygen or sulfur; and wherein R5 is phenyl; phenyl substituted with one or two substituent groups selected from chlorine, bromine, fluorine, (C1-C3)alkoxy or (C1-C3)alkyl; 2-thiophene; or 3-thiophene; with the proviso that when R3 contains more than four carbon atoms and R4 is alkyl said alkyl contains from one to 3 carbon atoms.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIjxTc1LLUnNyT28RKEktSixILW0pCSzOLW4JFMh-_CSypKSw9uyU3MK8jOLS1LzFIx0E3Mz8_JLUkuKEnMyM_Mys_IzUhLz8hIh0mWJOblAFlBNcWp2cSYPA2taYk5xKi-U5mZQcHMNcfbQTS3Ij08tLkhMBlke7-ZpaGBkYWns5GRoTIQSAJlNP84</recordid><startdate>19990315</startdate><enddate>19990315</enddate><creator>SVENSSON, KJELL ANDERS IVAN</creator><creator>CARLSSON, PER ARVID EMIL</creator><creator>WIKSTROEM, HAAKAN VILHELM</creator><creator>ANDERSSON, BENGT RONNY</creator><scope>EVB</scope></search><sort><creationdate>19990315</creationdate><title>Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi</title><author>SVENSSON, KJELL ANDERS IVAN ; CARLSSON, PER ARVID EMIL ; WIKSTROEM, HAAKAN VILHELM ; ANDERSSON, BENGT RONNY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_FI102893BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>fin ; swe</language><creationdate>1999</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SVENSSON, KJELL ANDERS IVAN</creatorcontrib><creatorcontrib>CARLSSON, PER ARVID EMIL</creatorcontrib><creatorcontrib>WIKSTROEM, HAAKAN VILHELM</creatorcontrib><creatorcontrib>ANDERSSON, BENGT RONNY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SVENSSON, KJELL ANDERS IVAN</au><au>CARLSSON, PER ARVID EMIL</au><au>WIKSTROEM, HAAKAN VILHELM</au><au>ANDERSSON, BENGT RONNY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi</title><date>1999-03-15</date><risdate>1999</risdate><abstract>This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula wherein -YR1 is one substituent on the 5, 6, 7 or 8 position of the aromatic ring, and is -S(C1-C3)alkyl or OR1 wherein R1 is selected from the group consisting of (C1-C8) alkyl, (C1-C8) alkenyl,- CH2-(C3-C8) cycloalkyl or benzyl; wherein R2 is hydrogen or (C1-C3) alkyl; wherein R3 is -CH2-(C3-C8) cycloalkyl; wherein R4 is hydrogen, (C1-C8) alkyl, -CH2-(C3-C4) cycloalkyl -(CH2)m-R5 or -CH2-CH2-X-(CH2)nCH3; wherein n is zero to 3 and m is 2 or 3; wherein X is oxygen or sulfur; and wherein R5 is phenyl; phenyl substituted with one or two substituent groups selected from chlorine, bromine, fluorine, (C1-C3)alkoxy or (C1-C3)alkyl; 2-thiophene; or 3-thiophene; with the proviso that when R3 contains more than four carbon atoms and R4 is alkyl said alkyl contains from one to 3 carbon atoms.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | fin ; swe |
| recordid | cdi_epo_espacenet_FI102893BB1 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Menetelmä terapeuttisesti käyttökelpoisten 2-aminotetraliinijohdannaisten valmistamiseksi |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T05%3A02%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SVENSSON,%20KJELL%20ANDERS%20IVAN&rft.date=1999-03-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EFI102893BB1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |