Inhibidores de IRE-1A
Compuesto o sal farmacéuticamente aceptable del mismo, en el que el compuesto inhibe directamente la actividad de IRE-1α in vitro y se selecciona entre: **(Tabla)** Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and...
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| creator | WADE, Warren Stanfield ZENG, Qingping ZUBOVICS, Zoltan YANG, Yun PATTERSON, John Bruce WU, Zhipeng TORO, Andras |
| description | Compuesto o sal farmacéuticamente aceptable del mismo, en el que el compuesto inhibe directamente la actividad de IRE-1α in vitro y se selecciona entre: **(Tabla)**
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies. |
| format | Patent |
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Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Inhibidores de IRE-1A |
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