QUIMERA SINTETICA MULTIEPITOPICA COMO VACUNA Y TRATAMIENTO FRENTE A LEISHMANIOSIS EN MAMIFEROS

Synthetic chimera which includes four multi-epitope peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are nucleosomal histones H2A, H2B, H3 and H4. The invention also relates to a pharmaceutical composition which includes the synthetic chim...

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Hauptverfasser: CARRION HERRERO, FRANCISCO JAVIER, DOMINGUEZ BERNAL, GUSTAVO, MAS ZUBIRI, ALICIA, DE LA FUENTE LOPEZ, RICARDO, MARTINEZ RODRIGO, ABEL, ORDEN GUTIERREZ, JOSE ANTONIO
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creator CARRION HERRERO, FRANCISCO JAVIER
DOMINGUEZ BERNAL, GUSTAVO
MAS ZUBIRI, ALICIA
DE LA FUENTE LOPEZ, RICARDO
MARTINEZ RODRIGO, ABEL
ORDEN GUTIERREZ, JOSE ANTONIO
description Synthetic chimera which includes four multi-epitope peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are nucleosomal histones H2A, H2B, H3 and H4. The invention also relates to a pharmaceutical composition which includes the synthetic chimera. It also concerns a prophylactic and/or therapeutic vaccine against Leishmania spp. for use in mammals and especially in humans and dogs.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title QUIMERA SINTETICA MULTIEPITOPICA COMO VACUNA Y TRATAMIENTO FRENTE A LEISHMANIOSIS EN MAMIFEROS
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