SYNTHETIC MULTIEPITOPIC CHIMERA AS VACCINE AND TREATMENT AGAINST LEISHMANIOSIS IN MAMMALS (Machine-translation by Google Translate, not legally binding)

Synthetic multiepitopic chimera as a vaccine and treatment against leishmaniasis in mammals. The invention relates to synthetic chimeras including 4 multiepitopic peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are the nucleosomal histone...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CARRION HERRERO, FRANCISCO JAVIER, DOMINGUEZ BERNAL, GUSTAVO, MAS ZUBIRI, ALICIA, DE LA FUENTE LOPEZ, RICARDO, MARTINEZ RODRIGO, ABEL, ORDEN GUTIERREZ, JOSE ANTONIO
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Synthetic multiepitopic chimera as a vaccine and treatment against leishmaniasis in mammals. The invention relates to synthetic chimeras including 4 multiepitopic peptides against Leishmania. Each of the peptides has been selected from a Leishmania infantum protein. These are the nucleosomal histones H2A, H2B, H3 and H4. The invention also relates to a pharmaceutical composition that includes one of these synthetic chimeras. It also refers to a prophylactic and/or therapeutic vaccine against Leishmania spp for use in mammals and especially in humans and dogs. (Machine-translation by Google Translate, not legally binding) Quimera sintética multiepitópica como vacuna y tratamiento frente a leishmaniosis en mamíferos. La invención se refiere a quimeras sintéticas que incluyen 4 péptidos multiepitópicos frente a Leishmania. Cada uno de los péptidos se ha seleccionado de una proteína de Leishmania infantum. Se trata de las histonas nucleosomales H2A, H2B, H3 y H4. La invención también se refiere a una composición farmacéutica que incluye una de estas quimeras sintéticas. También se refiere a una vacuna profiláctica y/o terapéutica frente a Leishmania spp para su uso en mamíferos y, especialmente, en humana y en perros.