Activación de CD89 en terapia
Una molécula activadora de CD89 para su uso en el tratamiento de una afección inflamatoria o un trastorno autoinmunitario, mediante la inducción de la apoptosis en neutrófilos, donde la molécula activadora de CD89 es una molécula que comprende Fc alfa, que se administra como una solución estéril. Th...
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| creator | MIESCHER, Sylvia VON GUNTEN, Stephan ZÜRCHER, Adrian WEHRLI, Marc |
| description | Una molécula activadora de CD89 para su uso en el tratamiento de una afección inflamatoria o un trastorno autoinmunitario, mediante la inducción de la apoptosis en neutrófilos, donde la molécula activadora de CD89 es una molécula que comprende Fc alfa, que se administra como una solución estéril.
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis. |
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The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.</description><language>spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180504&DB=EPODOC&CC=ES&NR=2666397T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180504&DB=EPODOC&CC=ES&NR=2666397T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MIESCHER, Sylvia</creatorcontrib><creatorcontrib>VON GUNTEN, Stephan</creatorcontrib><creatorcontrib>ZÜRCHER, Adrian</creatorcontrib><creatorcontrib>WEHRLI, Marc</creatorcontrib><title>Activación de CD89 en terapia</title><description>Una molécula activadora de CD89 para su uso en el tratamiento de una afección inflamatoria o un trastorno autoinmunitario, mediante la inducción de la apoptosis en neutrófilos, donde la molécula activadora de CD89 es una molécula que comprende Fc alfa, que se administra como una solución estéril.
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBzTC7JLEtMzjy8OU8hJVXB2cXCUiE1T6EktSixIDORh4E1LTGnOJUXSnMzKLq5hjh76KYW5MenFhckJqfmpZbEuwYbmZmZGVuah4QYGxOjBgDb8CSX</recordid><startdate>20180504</startdate><enddate>20180504</enddate><creator>MIESCHER, Sylvia</creator><creator>VON GUNTEN, Stephan</creator><creator>ZÜRCHER, Adrian</creator><creator>WEHRLI, Marc</creator><scope>EVB</scope></search><sort><creationdate>20180504</creationdate><title>Activación de CD89 en terapia</title><author>MIESCHER, Sylvia ; VON GUNTEN, Stephan ; ZÜRCHER, Adrian ; WEHRLI, Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2666397TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MIESCHER, Sylvia</creatorcontrib><creatorcontrib>VON GUNTEN, Stephan</creatorcontrib><creatorcontrib>ZÜRCHER, Adrian</creatorcontrib><creatorcontrib>WEHRLI, Marc</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MIESCHER, Sylvia</au><au>VON GUNTEN, Stephan</au><au>ZÜRCHER, Adrian</au><au>WEHRLI, Marc</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Activación de CD89 en terapia</title><date>2018-05-04</date><risdate>2018</risdate><abstract>Una molécula activadora de CD89 para su uso en el tratamiento de una afección inflamatoria o un trastorno autoinmunitario, mediante la inducción de la apoptosis en neutrófilos, donde la molécula activadora de CD89 es una molécula que comprende Fc alfa, que se administra como una solución estéril.
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Activación de CD89 en terapia |
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