Método de extracción de exosomas y dispositivo microfluídico de extracción de exosomas

Método de extracción de exosomas y dispositivo microfluídico de extracción de exosomas

Method for extracting exosomes depending on their diameter, comprising a step of introducing a fluid sample comprising at least two exosome populations, each with a different diameter, in a microfluidic device (10) comprising at least one channel (1) comprising at least one inlet (2) for the fluid s...

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Hauptverfasser: ILORO MANZANO, Ibon, ERRARTE YARZA, Ane, AGINAGALDE UNANUE, Maialen, ELORTZA BASTERRIKA, Felix Roberto, GONZALEZ JIMENEZ, Maria Esperanza, BOUALI SAIDI, Mohammed Mounir, MARTIN MAYOR, Alain, FALCON PEREZ, Juan Manuel
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INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator ILORO MANZANO, Ibon
ERRARTE YARZA, Ane
AGINAGALDE UNANUE, Maialen
ELORTZA BASTERRIKA, Felix Roberto
GONZALEZ JIMENEZ, Maria Esperanza
BOUALI SAIDI, Mohammed Mounir
MARTIN MAYOR, Alain
FALCON PEREZ, Juan Manuel
description Method for extracting exosomes depending on their diameter, comprising a step of introducing a fluid sample comprising at least two exosome populations, each with a different diameter, in a microfluidic device (10) comprising at least one channel (1) comprising at least one inlet (2) for the fluid sample and at least two openings (3) distributed along the channel (1) allowing the exosome populations to move out and an outlet (5) for the remaining fluid sample, and means (6) for generating a temperature gradient in the channel (1); and a step in which the fluid sample is made to flow through the channel (1) while a temperature gradient is applied on the channel, causing each population to move out through a different opening (3). The present invention also relates to a microfluidic device (10) for the application of the method.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Método de extracción de exosomas y dispositivo microfluídico de extracción de exosomas
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