Ligadores basados en tirosina para la conexión desprendible de péptidos
Un compuesto de fórmula**Fórmula** en la que n representa el número 0, 1, 2, 3 o 4, m representa el número 0, 1, 2, 3 o 4, en la que m y n son juntos son el número 1, 2, 3, 4, 5 o 6, R1 representa terc-butiloxicarbonilo o (9H-fluoren-9-ilmetoxi)carbonilo, R2 representa terc-butiloxicarbonilo, R3 rep...
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| creator | KRENZ, Ursula KÖBBERLING, Johannes LERCHEN, Hans-Georg WITTROCK, Sven GRIEBENOW, Nils FLAMME, Ingo SCHOHE-LOOP, Rudolf |
| description | Un compuesto de fórmula**Fórmula** en la que n representa el número 0, 1, 2, 3 o 4, m representa el número 0, 1, 2, 3 o 4, en la que m y n son juntos son el número 1, 2, 3, 4, 5 o 6, R1 representa terc-butiloxicarbonilo o (9H-fluoren-9-ilmetoxi)carbonilo, R2 representa terc-butiloxicarbonilo, R3 representa hidrógeno, metilo, etilo, n-propilo, isopropilo o bencilo, R4 representa un grupo de fórmula
The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases. |
| format | Patent |
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The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.</description><language>spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170717&DB=EPODOC&CC=ES&NR=2624626T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170717&DB=EPODOC&CC=ES&NR=2624626T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KRENZ, Ursula</creatorcontrib><creatorcontrib>KÖBBERLING, Johannes</creatorcontrib><creatorcontrib>LERCHEN, Hans-Georg</creatorcontrib><creatorcontrib>WITTROCK, Sven</creatorcontrib><creatorcontrib>GRIEBENOW, Nils</creatorcontrib><creatorcontrib>FLAMME, Ingo</creatorcontrib><creatorcontrib>SCHOHE-LOOP, Rudolf</creatorcontrib><title>Ligadores basados en tirosina para la conexión desprendible de péptidos</title><description>Un compuesto de fórmula**Fórmula** en la que n representa el número 0, 1, 2, 3 o 4, m representa el número 0, 1, 2, 3 o 4, en la que m y n son juntos son el número 1, 2, 3, 4, 5 o 6, R1 representa terc-butiloxicarbonilo o (9H-fluoren-9-ilmetoxi)carbonilo, R2 representa terc-butiloxicarbonilo, R3 representa hidrógeno, metilo, etilo, n-propilo, isopropilo o bencilo, R4 representa un grupo de fórmula
The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPD0yUxPTMkvSi1WSEosBrKKFVLzFEoyi_KLM_MSFQoSixIVchIVkvPzUisyD2_OU0hJLS4oSs1LyUzKSQVyFAoOrywoyQTq42FgTUvMKU7lhdLcDIpuriHOHrqpBfnxQE2Jyal5qSXxrsFGZkYmZkZmISHGxsSoAQB4pTaB</recordid><startdate>20170717</startdate><enddate>20170717</enddate><creator>KRENZ, Ursula</creator><creator>KÖBBERLING, Johannes</creator><creator>LERCHEN, Hans-Georg</creator><creator>WITTROCK, Sven</creator><creator>GRIEBENOW, Nils</creator><creator>FLAMME, Ingo</creator><creator>SCHOHE-LOOP, Rudolf</creator><scope>EVB</scope></search><sort><creationdate>20170717</creationdate><title>Ligadores basados en tirosina para la conexión desprendible de péptidos</title><author>KRENZ, Ursula ; KÖBBERLING, Johannes ; LERCHEN, Hans-Georg ; WITTROCK, Sven ; GRIEBENOW, Nils ; FLAMME, Ingo ; SCHOHE-LOOP, Rudolf</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2624626TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KRENZ, Ursula</creatorcontrib><creatorcontrib>KÖBBERLING, Johannes</creatorcontrib><creatorcontrib>LERCHEN, Hans-Georg</creatorcontrib><creatorcontrib>WITTROCK, Sven</creatorcontrib><creatorcontrib>GRIEBENOW, Nils</creatorcontrib><creatorcontrib>FLAMME, Ingo</creatorcontrib><creatorcontrib>SCHOHE-LOOP, Rudolf</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRENZ, Ursula</au><au>KÖBBERLING, Johannes</au><au>LERCHEN, Hans-Georg</au><au>WITTROCK, Sven</au><au>GRIEBENOW, Nils</au><au>FLAMME, Ingo</au><au>SCHOHE-LOOP, Rudolf</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Ligadores basados en tirosina para la conexión desprendible de péptidos</title><date>2017-07-17</date><risdate>2017</risdate><abstract>Un compuesto de fórmula**Fórmula** en la que n representa el número 0, 1, 2, 3 o 4, m representa el número 0, 1, 2, 3 o 4, en la que m y n son juntos son el número 1, 2, 3, 4, 5 o 6, R1 representa terc-butiloxicarbonilo o (9H-fluoren-9-ilmetoxi)carbonilo, R2 representa terc-butiloxicarbonilo, R3 representa hidrógeno, metilo, etilo, n-propilo, isopropilo o bencilo, R4 representa un grupo de fórmula
The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Ligadores basados en tirosina para la conexión desprendible de péptidos |
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