Formas cristalinas de un inhibidor del Factor Xa
Una forma cristalina del maleato de betrixabán que tiene: i) un patrón de difracción de rayos X en polvo parecido al patrón de difracción de rayos X en polvo mostrado en la Figura 2 o 3; o iv) una estructura de celda unitaria con los siguientes parámetros de la celda a 100 K: a >= 8,284 Å, b >...
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| creator | MARGELEFSKY, Eric CAPODANNO, Vincent WENSLOW, Robert MAHER, Timothy ARROYO, Itzia Zoraida CORCORAN, Liam McNEVIN, Michael BALL, Richard PANDEY, Anjali |
| description | Una forma cristalina del maleato de betrixabán que tiene: i) un patrón de difracción de rayos X en polvo parecido al patrón de difracción de rayos X en polvo mostrado en la Figura 2 o 3; o iv) una estructura de celda unitaria con los siguientes parámetros de la celda a 100 K: a >= 8,284 Å, b >= 18,082 Å, c >= 18,681 Å, α >= 71,22 º, ß >= 86,76 º, γ >= 89,69 º, y V >= 2645 A3; o v) una estructura de celda unitaria con los siguientes parámetros de la celda a 273 K: a >= 8,419 Å, b >= 18,113 Å, c >= 18,73 Å, α >= 71,14 º, ß >= 86,71 º, γ >= 89,31 º, y V >= 2699 A3.
Provided herein are crystalline forms of a maleate salt of betrixaban, compositions and methods of preparation or use thereof. |
| format | Patent |
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Provided herein are crystalline forms of a maleate salt of betrixaban, compositions and methods of preparation or use thereof.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Formas cristalinas de un inhibidor del Factor Xa |
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