Bacterial strain of pseudonocardia carboxydivorans producer of branimycins and branimycins produced by the same (Machine-translation by Google Translate, not legally binding)

Bacterial strain of pseudonocardia carboxydivorans producer of branimycins and branimycins produced by it. The invention provides a new bacterial strain of pseudonocardia carboxydivorans that has been isolated from its natural environment and deposited in the spanish collection of type cultures unde...

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Hauptverfasser: BLANCO BLANCO, María Gloria, REYES BENITEZ, José Fernando, FERNANDEZ BRANA, Alfredo Javier, PEREZ-VICTORIA MORENO DE BARREDA, Ignacio, PALACIOS GUTIERREZ, Juan José, GARCIA DIAZ, Luis Arsenio, FERNANDEZ SUAREZ, Jonathan, MARTIN SERRANO, Jesús Melchor, SARMIENTO VIZCAINO, Aida, OTERO GUERRA, Luis
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Bacterial strain of pseudonocardia carboxydivorans producer of branimycins and branimycins produced by it. The invention provides a new bacterial strain of pseudonocardia carboxydivorans that has been isolated from its natural environment and deposited in the spanish collection of type cultures under the accession number 9108, which is able to efficiently produce by fermentation antibiotic compounds of the family of the branimicines. Specifically, this strain is the producer of two new branimicines, designated in the present invention as branimicins b and c, which present antibiotic or antibacterial activity in vitro and in vivo against pathogenic bacteria, preferably human, both gram positive and gram negative, preferably resistant. To the antibiotics of habitual use. (Machine-translation by Google Translate, not legally binding) Cepa bacteriana de Pseudonocardia carboxydivorans productora de branimicinas y branimicinas producidas por la misma. La invención proporciona una nueva cepa bacteriana de Pseudonocardia carboxydivorans que ha sido aislada de su medio natural y depositada en la colección española de cultivos tipo bajo el número de acceso 9108, la cual es capaz de producir eficientemente por fermentación compuestos antibióticos de la familia de las branimicinas. Concretamente, esta cepa es productora de dos nuevas branimicinas, designadas en la presente invención como branimicinas B y C, que presentan actividad antibiótica o antibacteriana in vitro e in vivo frente a bacterias patógenas, preferiblemente humanas, tanto Gram positivas como Gram negativas, preferiblemente resistentes a los antibióticos de uso habitual.