HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND

The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, sal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ADRIO FONDEVILA, JOSE LUIS, SIERRA AVILA, SALETA, RAMOS MARTIN, MARIA DEL CARMEN, ALFARO SANCHEZ, JUAN MARIA, RAMIREZ MORENO, CARLOS, VELASCO ALVAREZ, JAVIER, BURGOS MUNOZ, JAVIER SANTOS
Format: Patent
Sprache:eng ; spa
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator ADRIO FONDEVILA, JOSE LUIS
SIERRA AVILA, SALETA
RAMOS MARTIN, MARIA DEL CARMEN
ALFARO SANCHEZ, JUAN MARIA
RAMIREZ MORENO, CARLOS
VELASCO ALVAREZ, JAVIER
BURGOS MUNOZ, JAVIER SANTOS
description The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for use in the prevention of: neurodegenerative diseases, cognitive impairment, diseases associated with undesired oxidation, age-associated pathological processes and progeria, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipidemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, inflammation or inflammatory processes, or epilepsy, epileptic seizures and convulsions. Se describe un compuesto de fórmula (I)***IMAGEN***su forma hidroxiácida, las sales farmacéuticamente aceptables de dicho hidroxiácido y prodrogas y solvatos farmacéuticamente aceptables del compuesto y de su forma hidroxiácida y, en particular, dicho compuesto, su forma hidroxiácida, sales, etc. para su uso en la prevención de: enfermedades neurodegenerativas, deterioro cognitivo, enfermedades asociadas con una oxidación indeseada, procesos patológicos asociados a la edad y progeria, enfermedades cardiovasculares como aterosclerosis, fibrilación auricular, dislipemia, hipercolesterolemia, hiperlipidemia, e hipertrigliceridemia, o inflamación o procesos inflamatorios, o epilepsia, crisis epilépticas y convulsiones.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ES2380473A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ES2380473A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ES2380473A13</originalsourceid><addsrcrecordid>eNrjZAj0iAzwd_bw93ENDnENAlK-ns46Co5-IZ66nn5uPo6-vo4h_kGRQBEXsKhrgKePa0CIp7OCn2tokH9AkH-Iq3OIZ5irgrO_b4B_qJ8LDwNrWmJOcSovlOZmUHBzDXH20E0tyI9PLS5ITE7NSy2Jdw02MrYwMDE3djQ0JkIJAK6zL8c</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND</title><source>esp@cenet</source><creator>ADRIO FONDEVILA, JOSE LUIS ; SIERRA AVILA, SALETA ; RAMOS MARTIN, MARIA DEL CARMEN ; ALFARO SANCHEZ, JUAN MARIA ; RAMIREZ MORENO, CARLOS ; VELASCO ALVAREZ, JAVIER ; BURGOS MUNOZ, JAVIER SANTOS</creator><creatorcontrib>ADRIO FONDEVILA, JOSE LUIS ; SIERRA AVILA, SALETA ; RAMOS MARTIN, MARIA DEL CARMEN ; ALFARO SANCHEZ, JUAN MARIA ; RAMIREZ MORENO, CARLOS ; VELASCO ALVAREZ, JAVIER ; BURGOS MUNOZ, JAVIER SANTOS</creatorcontrib><description>The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for use in the prevention of: neurodegenerative diseases, cognitive impairment, diseases associated with undesired oxidation, age-associated pathological processes and progeria, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipidemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, inflammation or inflammatory processes, or epilepsy, epileptic seizures and convulsions. Se describe un compuesto de fórmula (I)***IMAGEN***su forma hidroxiácida, las sales farmacéuticamente aceptables de dicho hidroxiácido y prodrogas y solvatos farmacéuticamente aceptables del compuesto y de su forma hidroxiácida y, en particular, dicho compuesto, su forma hidroxiácida, sales, etc. para su uso en la prevención de: enfermedades neurodegenerativas, deterioro cognitivo, enfermedades asociadas con una oxidación indeseada, procesos patológicos asociados a la edad y progeria, enfermedades cardiovasculares como aterosclerosis, fibrilación auricular, dislipemia, hipercolesterolemia, hiperlipidemia, e hipertrigliceridemia, o inflamación o procesos inflamatorios, o epilepsia, crisis epilépticas y convulsiones.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20120514&amp;DB=EPODOC&amp;CC=ES&amp;NR=2380473A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20120514&amp;DB=EPODOC&amp;CC=ES&amp;NR=2380473A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ADRIO FONDEVILA, JOSE LUIS</creatorcontrib><creatorcontrib>SIERRA AVILA, SALETA</creatorcontrib><creatorcontrib>RAMOS MARTIN, MARIA DEL CARMEN</creatorcontrib><creatorcontrib>ALFARO SANCHEZ, JUAN MARIA</creatorcontrib><creatorcontrib>RAMIREZ MORENO, CARLOS</creatorcontrib><creatorcontrib>VELASCO ALVAREZ, JAVIER</creatorcontrib><creatorcontrib>BURGOS MUNOZ, JAVIER SANTOS</creatorcontrib><title>HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND</title><description>The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for use in the prevention of: neurodegenerative diseases, cognitive impairment, diseases associated with undesired oxidation, age-associated pathological processes and progeria, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipidemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, inflammation or inflammatory processes, or epilepsy, epileptic seizures and convulsions. Se describe un compuesto de fórmula (I)***IMAGEN***su forma hidroxiácida, las sales farmacéuticamente aceptables de dicho hidroxiácido y prodrogas y solvatos farmacéuticamente aceptables del compuesto y de su forma hidroxiácida y, en particular, dicho compuesto, su forma hidroxiácida, sales, etc. para su uso en la prevención de: enfermedades neurodegenerativas, deterioro cognitivo, enfermedades asociadas con una oxidación indeseada, procesos patológicos asociados a la edad y progeria, enfermedades cardiovasculares como aterosclerosis, fibrilación auricular, dislipemia, hipercolesterolemia, hiperlipidemia, e hipertrigliceridemia, o inflamación o procesos inflamatorios, o epilepsia, crisis epilépticas y convulsiones.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAj0iAzwd_bw93ENDnENAlK-ns46Co5-IZ66nn5uPo6-vo4h_kGRQBEXsKhrgKePa0CIp7OCn2tokH9AkH-Iq3OIZ5irgrO_b4B_qJ8LDwNrWmJOcSovlOZmUHBzDXH20E0tyI9PLS5ITE7NSy2Jdw02MrYwMDE3djQ0JkIJAK6zL8c</recordid><startdate>20120514</startdate><enddate>20120514</enddate><creator>ADRIO FONDEVILA, JOSE LUIS</creator><creator>SIERRA AVILA, SALETA</creator><creator>RAMOS MARTIN, MARIA DEL CARMEN</creator><creator>ALFARO SANCHEZ, JUAN MARIA</creator><creator>RAMIREZ MORENO, CARLOS</creator><creator>VELASCO ALVAREZ, JAVIER</creator><creator>BURGOS MUNOZ, JAVIER SANTOS</creator><scope>EVB</scope></search><sort><creationdate>20120514</creationdate><title>HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND</title><author>ADRIO FONDEVILA, JOSE LUIS ; SIERRA AVILA, SALETA ; RAMOS MARTIN, MARIA DEL CARMEN ; ALFARO SANCHEZ, JUAN MARIA ; RAMIREZ MORENO, CARLOS ; VELASCO ALVAREZ, JAVIER ; BURGOS MUNOZ, JAVIER SANTOS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2380473A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ADRIO FONDEVILA, JOSE LUIS</creatorcontrib><creatorcontrib>SIERRA AVILA, SALETA</creatorcontrib><creatorcontrib>RAMOS MARTIN, MARIA DEL CARMEN</creatorcontrib><creatorcontrib>ALFARO SANCHEZ, JUAN MARIA</creatorcontrib><creatorcontrib>RAMIREZ MORENO, CARLOS</creatorcontrib><creatorcontrib>VELASCO ALVAREZ, JAVIER</creatorcontrib><creatorcontrib>BURGOS MUNOZ, JAVIER SANTOS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ADRIO FONDEVILA, JOSE LUIS</au><au>SIERRA AVILA, SALETA</au><au>RAMOS MARTIN, MARIA DEL CARMEN</au><au>ALFARO SANCHEZ, JUAN MARIA</au><au>RAMIREZ MORENO, CARLOS</au><au>VELASCO ALVAREZ, JAVIER</au><au>BURGOS MUNOZ, JAVIER SANTOS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND</title><date>2012-05-14</date><risdate>2012</risdate><abstract>The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for use in the prevention of: neurodegenerative diseases, cognitive impairment, diseases associated with undesired oxidation, age-associated pathological processes and progeria, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipidemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, inflammation or inflammatory processes, or epilepsy, epileptic seizures and convulsions. Se describe un compuesto de fórmula (I)***IMAGEN***su forma hidroxiácida, las sales farmacéuticamente aceptables de dicho hidroxiácido y prodrogas y solvatos farmacéuticamente aceptables del compuesto y de su forma hidroxiácida y, en particular, dicho compuesto, su forma hidroxiácida, sales, etc. para su uso en la prevención de: enfermedades neurodegenerativas, deterioro cognitivo, enfermedades asociadas con una oxidación indeseada, procesos patológicos asociados a la edad y progeria, enfermedades cardiovasculares como aterosclerosis, fibrilación auricular, dislipemia, hipercolesterolemia, hiperlipidemia, e hipertrigliceridemia, o inflamación o procesos inflamatorios, o epilepsia, crisis epilépticas y convulsiones.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; spa
recordid cdi_epo_espacenet_ES2380473A1
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T03%3A13%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ADRIO%20FONDEVILA,%20JOSE%20LUIS&rft.date=2012-05-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EES2380473A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true