GHRELIN VARIANT AND USES THEREOF

The invention relates to a novel splicing variant of ghrelin/obestatin, called In2-ghrelin, and to the use alone and/or in combination with ghrelin-O-acyltransferase (GOAT) and/or the truncated ghrelin receptor (GHS-R1b), for obtaining useful data in the diagnosis, prognosis and monitoring of breast...

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Hauptverfasser: GRACIA NAVARRO, FRANCISCO, KINEMAN, RHONDA DENISSE, BENITO LOPEZ, PEDRO, CASTANO FUENTES, JUSTO PASTOR, LUQUE HUERTAS, RAUL MIGUEL, GAHETE ORTIZ, MANUEL DAVID, MARTINEZ FUENTES, ANTONIO JESUS, CORDOBA CHACON, JOSE
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The invention relates to a novel splicing variant of ghrelin/obestatin, called In2-ghrelin, and to the use alone and/or in combination with ghrelin-O-acyltransferase (GOAT) and/or the truncated ghrelin receptor (GHS-R1b), for obtaining useful data in the diagnosis, prognosis and monitoring of breast cancer, hypophysis tumours, and tumours of the ovary, endometrium and cervix. Variante de la ghrelina y sus usos.La presente invención se refiere a una nueva variante de splicing de la ghrelina/obestatina, denominada In2-ghrelina, y a su uso de manera aislada y/o en combinación con la ghrelin-O-aciltransferasa (GOAT) y/o el receptor truncado de ghrelina (GHS-R1b), para la obtención de datos útiles en el diagnóstico, pronóstico y seguimiento del cáncer de mama, de tumores hipofisarios, tumores de ovario, de endometrio y de cérvix.