Nitric oxide synthase inhibitor for use in treatment of inflammatory processes and as neuroprotector for animals and humans, is carboxamide compound showing biological properties as inhibitors of different isoforms of nitric oxide synthase

The nitric oxide synthase inhibitor is 5-(2,5-disubstituted phenyl)-1-disubstituted-1H-pyrrole-2-N-substituted-carboxamide, which shows biological properties as inhibitors of different isoforms of the nitric oxide synthase enzyme. ACTIVITY : Neuroprotective Antiinflammatory. MECHANISM OF ACTION : Ni...

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Hauptverfasser: GALLO MEZO MIGUEL ANGEL, ACUNA CASTROVIEJO DARIO, ESPIN0SA UBEDA ANTONIO, ENTRENA GUADIX ANTONIO JOSE, CAMACHO QUESADA ENCARNACION, GERMAINE ESCAMES ROSA
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creator GALLO MEZO MIGUEL ANGEL
ACUNA CASTROVIEJO DARIO
ESPIN0SA UBEDA ANTONIO
ENTRENA GUADIX ANTONIO JOSE
CAMACHO QUESADA ENCARNACION
GERMAINE ESCAMES ROSA
description The nitric oxide synthase inhibitor is 5-(2,5-disubstituted phenyl)-1-disubstituted-1H-pyrrole-2-N-substituted-carboxamide, which shows biological properties as inhibitors of different isoforms of the nitric oxide synthase enzyme. ACTIVITY : Neuroprotective Antiinflammatory. MECHANISM OF ACTION : Nitric oxide synthase inhibitor. 3-benzoilpirazoles inhibidores de la óxido nítrico sintasa (NOS) con actividad neuroprotectora, identificados como 3-(2,5-disustituido-benzoil)-1-sustituido-4,5-dihidro-1H-pirazol-5-carboxilato de etilo y 3-(2,5-disustituido-benzoil)-1-sustituido-1H-pirazol-5-carboxilato de etilo, que muestran interesantes propiedades biológicas como inhibidores de distintas isoformas de la enzima oxido nítrico sintasa (NOS) y que, consecuentemente, encuentran aplicación en el tratamiento de procesos inflamatorios y por su capacidad neuroprotectora, para poder ser usados en animales y humanos.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Nitric oxide synthase inhibitor for use in treatment of inflammatory processes and as neuroprotector for animals and humans, is carboxamide compound showing biological properties as inhibitors of different isoforms of nitric oxide synthase
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