TRATAMIENTO TERAPEUTICO PARA ENFERMEDADES CARDIOVASCULARES
SE PRESENTA UN PROCEDIMIENTO PARA TRATAR LAS DISFUNCIONES DE LAS CELULAS ENDOTELIALES, TALES COMO LAS ASOCIADAS CON LAS ENFERMEDADES CARDIOVASCULARES, PARTICULARMENTE UTILIZANDO EL INHIBIDOR DE LA PKC SELECTIVO A LAS ISOENZIMAS, SAL DE HIDROCLORURO DE (S)-3,4-[N,N''-1,1''-((27&qu...
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| creator | WAYS, DOUGLAS, KIRK JIROUSEK, MICHAEL, R STRAMM, LAWRENCE, E HEATH, WILLIAM, FRANCIS, JR |
| description | SE PRESENTA UN PROCEDIMIENTO PARA TRATAR LAS DISFUNCIONES DE LAS CELULAS ENDOTELIALES, TALES COMO LAS ASOCIADAS CON LAS ENFERMEDADES CARDIOVASCULARES, PARTICULARMENTE UTILIZANDO EL INHIBIDOR DE LA PKC SELECTIVO A LAS ISOENZIMAS, SAL DE HIDROCLORURO DE (S)-3,4-[N,N''-1,1''-((27"-ETOXIDO)-3''"(O)-4''"(N,N-DIMETILAMINO)-BUTANO)-BIS-(3,3''INDOLIL)]-1(H)-PIRROLA-2,5DIONA.
A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((27''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt. |
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A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((27''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt.</description><edition>7</edition><language>spa</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060616&DB=EPODOC&CC=ES&NR=2255106T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060616&DB=EPODOC&CC=ES&NR=2255106T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WAYS, DOUGLAS, KIRK</creatorcontrib><creatorcontrib>JIROUSEK, MICHAEL, R</creatorcontrib><creatorcontrib>STRAMM, LAWRENCE, E</creatorcontrib><creatorcontrib>HEATH, WILLIAM, FRANCIS, JR</creatorcontrib><title>TRATAMIENTO TERAPEUTICO PARA ENFERMEDADES CARDIOVASCULARES</title><description>SE PRESENTA UN PROCEDIMIENTO PARA TRATAR LAS DISFUNCIONES DE LAS CELULAS ENDOTELIALES, TALES COMO LAS ASOCIADAS CON LAS ENFERMEDADES CARDIOVASCULARES, PARTICULARMENTE UTILIZANDO EL INHIBIDOR DE LA PKC SELECTIVO A LAS ISOENZIMAS, SAL DE HIDROCLORURO DE (S)-3,4-[N,N''-1,1''-((27"-ETOXIDO)-3''"(O)-4''"(N,N-DIMETILAMINO)-BUTANO)-BIS-(3,3''INDOLIL)]-1(H)-PIRROLA-2,5DIONA.
A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((27''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAKCXIMcfT1dPUL8VcIcQ1yDHANDfF09lcIcAxyVHD1c3MN8nV1cXRxDVZwdgxy8fQPcwx2DvVxDHIN5mFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8a7BRkampoYGZiEhxsbEqAEA6fQpzA</recordid><startdate>20060616</startdate><enddate>20060616</enddate><creator>WAYS, DOUGLAS, KIRK</creator><creator>JIROUSEK, MICHAEL, R</creator><creator>STRAMM, LAWRENCE, E</creator><creator>HEATH, WILLIAM, FRANCIS, JR</creator><scope>EVB</scope></search><sort><creationdate>20060616</creationdate><title>TRATAMIENTO TERAPEUTICO PARA ENFERMEDADES CARDIOVASCULARES</title><author>WAYS, DOUGLAS, KIRK ; JIROUSEK, MICHAEL, R ; STRAMM, LAWRENCE, E ; HEATH, WILLIAM, FRANCIS, JR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2255106TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2006</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WAYS, DOUGLAS, KIRK</creatorcontrib><creatorcontrib>JIROUSEK, MICHAEL, R</creatorcontrib><creatorcontrib>STRAMM, LAWRENCE, E</creatorcontrib><creatorcontrib>HEATH, WILLIAM, FRANCIS, JR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WAYS, DOUGLAS, KIRK</au><au>JIROUSEK, MICHAEL, R</au><au>STRAMM, LAWRENCE, E</au><au>HEATH, WILLIAM, FRANCIS, JR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TRATAMIENTO TERAPEUTICO PARA ENFERMEDADES CARDIOVASCULARES</title><date>2006-06-16</date><risdate>2006</risdate><abstract>SE PRESENTA UN PROCEDIMIENTO PARA TRATAR LAS DISFUNCIONES DE LAS CELULAS ENDOTELIALES, TALES COMO LAS ASOCIADAS CON LAS ENFERMEDADES CARDIOVASCULARES, PARTICULARMENTE UTILIZANDO EL INHIBIDOR DE LA PKC SELECTIVO A LAS ISOENZIMAS, SAL DE HIDROCLORURO DE (S)-3,4-[N,N''-1,1''-((27"-ETOXIDO)-3''"(O)-4''"(N,N-DIMETILAMINO)-BUTANO)-BIS-(3,3''INDOLIL)]-1(H)-PIRROLA-2,5DIONA.
A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N,N'-1,1'-((27''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TRATAMIENTO TERAPEUTICO PARA ENFERMEDADES CARDIOVASCULARES |
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