DERIVADOS DE IMIDAZOL
LOS DERIVADOS DEL IMIDAZOL DE FORMULA GENERAL (I), DONDE R{SUP,1} - R{SUP,8} SIGNIFICAN INDEPENDIENTEMENTE HIDROGENO, ALQUILO DE BAJO PESO MOLECULAR, ALQUILO DE BAJO PESO MOLECULAR SUSTITUIDO, ALQUENILO DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR SUSTITUIDO,...
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creator | KRASSO, ANNA KAMBER, MARKUS PIRSON, WOLFANG WYSS, PIERREARLES HARMON, CHARLES, STANFORD |
description | LOS DERIVADOS DEL IMIDAZOL DE FORMULA GENERAL (I), DONDE R{SUP,1} - R{SUP,8} SIGNIFICAN INDEPENDIENTEMENTE HIDROGENO, ALQUILO DE BAJO PESO MOLECULAR, ALQUILO DE BAJO PESO MOLECULAR SUSTITUIDO, ALQUENILO DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR SUSTITUIDO, ALCOXICARBONILO DE BAJO PESO MOLECULAR, HALOGENO, HIDROXI, AMINO, MONO O DI (ALQUIL DE BAJO PESO MOLECULAR) AMINO O NITRO. LAS SALES FARMACEUTICAMENTE UTILIZABLES DE ESTOS COMPUESTOS SON INHIBIDORES DE PROTEIN QUINASA Y SE PUEDEN USAR COMO MEDICAMENTOS, POR EJEMPLO, PARA EL CONTROL DE TRASTORNOS HIPERPROLIFERATIVOS COMO ARTERIOSCLEROSIS, PSORIASIS Y TUMORES, ASI COMO ALOPECIA.
PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3, R5, R7 and R8 are as disclosed herein. These compounds are protein kinase inhibitors useful in the treatment of atherosclerosis, psoriasis, alopecia, and tumors. |
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PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3, R5, R7 and R8 are as disclosed herein. These compounds are protein kinase inhibitors useful in the treatment of atherosclerosis, psoriasis, alopecia, and tumors.</description><edition>7</edition><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040616&DB=EPODOC&CC=ES&NR=2208698T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040616&DB=EPODOC&CC=ES&NR=2208698T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KRASSO, ANNA</creatorcontrib><creatorcontrib>KAMBER, MARKUS</creatorcontrib><creatorcontrib>PIRSON, WOLFANG</creatorcontrib><creatorcontrib>WYSS, PIERREARLES</creatorcontrib><creatorcontrib>HARMON, CHARLES, STANFORD</creatorcontrib><title>DERIVADOS DE IMIDAZOL</title><description>LOS DERIVADOS DEL IMIDAZOL DE FORMULA GENERAL (I), DONDE R{SUP,1} - R{SUP,8} SIGNIFICAN INDEPENDIENTEMENTE HIDROGENO, ALQUILO DE BAJO PESO MOLECULAR, ALQUILO DE BAJO PESO MOLECULAR SUSTITUIDO, ALQUENILO DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR SUSTITUIDO, ALCOXICARBONILO DE BAJO PESO MOLECULAR, HALOGENO, HIDROXI, AMINO, MONO O DI (ALQUIL DE BAJO PESO MOLECULAR) AMINO O NITRO. LAS SALES FARMACEUTICAMENTE UTILIZABLES DE ESTOS COMPUESTOS SON INHIBIDORES DE PROTEIN QUINASA Y SE PUEDEN USAR COMO MEDICAMENTOS, POR EJEMPLO, PARA EL CONTROL DE TRASTORNOS HIPERPROLIFERATIVOS COMO ARTERIOSCLEROSIS, PSORIASIS Y TUMORES, ASI COMO ALOPECIA.
PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3, R5, R7 and R8 are as disclosed herein. These compounds are protein kinase inhibitors useful in the treatment of atherosclerosis, psoriasis, alopecia, and tumors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB1cQ3yDHN08Q9WcHFV8PT1dHGM8vfhYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxrsFGRgYWZpYWISHGxsSoAQCXAB9H</recordid><startdate>20040616</startdate><enddate>20040616</enddate><creator>KRASSO, ANNA</creator><creator>KAMBER, MARKUS</creator><creator>PIRSON, WOLFANG</creator><creator>WYSS, PIERREARLES</creator><creator>HARMON, CHARLES, STANFORD</creator><scope>EVB</scope></search><sort><creationdate>20040616</creationdate><title>DERIVADOS DE IMIDAZOL</title><author>KRASSO, ANNA ; KAMBER, MARKUS ; PIRSON, WOLFANG ; WYSS, PIERREARLES ; HARMON, CHARLES, STANFORD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ES2208698TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2004</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KRASSO, ANNA</creatorcontrib><creatorcontrib>KAMBER, MARKUS</creatorcontrib><creatorcontrib>PIRSON, WOLFANG</creatorcontrib><creatorcontrib>WYSS, PIERREARLES</creatorcontrib><creatorcontrib>HARMON, CHARLES, STANFORD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRASSO, ANNA</au><au>KAMBER, MARKUS</au><au>PIRSON, WOLFANG</au><au>WYSS, PIERREARLES</au><au>HARMON, CHARLES, STANFORD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADOS DE IMIDAZOL</title><date>2004-06-16</date><risdate>2004</risdate><abstract>LOS DERIVADOS DEL IMIDAZOL DE FORMULA GENERAL (I), DONDE R{SUP,1} - R{SUP,8} SIGNIFICAN INDEPENDIENTEMENTE HIDROGENO, ALQUILO DE BAJO PESO MOLECULAR, ALQUILO DE BAJO PESO MOLECULAR SUSTITUIDO, ALQUENILO DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR, ALCOXI DE BAJO PESO MOLECULAR SUSTITUIDO, ALCOXICARBONILO DE BAJO PESO MOLECULAR, HALOGENO, HIDROXI, AMINO, MONO O DI (ALQUIL DE BAJO PESO MOLECULAR) AMINO O NITRO. LAS SALES FARMACEUTICAMENTE UTILIZABLES DE ESTOS COMPUESTOS SON INHIBIDORES DE PROTEIN QUINASA Y SE PUEDEN USAR COMO MEDICAMENTOS, POR EJEMPLO, PARA EL CONTROL DE TRASTORNOS HIPERPROLIFERATIVOS COMO ARTERIOSCLEROSIS, PSORIASIS Y TUMORES, ASI COMO ALOPECIA.
PCT No. PCT/EP95/04741 Sec. 371 Date Jun. 12, 1997 Sec. 102(e) Date Jun. 12, 1997 PCT Filed Dec. 1, 1995 PCT Pub. No. WO96/18626 PCT Pub. Date Jun. 20, 1996This invention relates to novel imidazole derivatives of formula a and pharmaceutically acceptable salts of these compounds, wherein R1, R2, R3, R5, R7 and R8 are as disclosed herein. These compounds are protein kinase inhibitors useful in the treatment of atherosclerosis, psoriasis, alopecia, and tumors.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | DERIVADOS DE IMIDAZOL |
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